Mental health resilience in offspring of depressed parents: a systematic literature review protocol

Abstract Background Parental depression is associated with a range of mental health conditions and other difficulties in the offspring. Nevertheless, some offspring exposed to parental depression do not develop mental health problems, indicating the presence of protective factors that may buffer par...

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Main Authors: Eglė Padaigaitė, Jessica Mayumi Maruyama, Gemma Hammerton, Frances Rice, Stephan Collishaw
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Systematic Reviews
Subjects:
Online Access:https://doi.org/10.1186/s13643-022-02056-6
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author Eglė Padaigaitė
Jessica Mayumi Maruyama
Gemma Hammerton
Frances Rice
Stephan Collishaw
author_facet Eglė Padaigaitė
Jessica Mayumi Maruyama
Gemma Hammerton
Frances Rice
Stephan Collishaw
author_sort Eglė Padaigaitė
collection DOAJ
description Abstract Background Parental depression is associated with a range of mental health conditions and other difficulties in the offspring. Nevertheless, some offspring exposed to parental depression do not develop mental health problems, indicating the presence of protective factors that may buffer parental depression-related risk effects. However, evidence of protective factors that might explain good sustained mental health in offspring of depressed parents is limited and systematic synthesis of these factors is still needed. Therefore, as far as we are aware, this will be the first systematic review that will identify parent, family, child, social, and lifestyle factors associated with mental health resilience in offspring of depressed parents, examine evidence for sex-, developmental stage-, and outcome-specific factors and define mental health resilience in the parental depression context. Methods This protocol has been developed according to the PRISMA-P guidelines. Electronic searches will be performed for articles published up to 2022 in PsycINFO, Embase, MEDLINE, Web of Science Core Collection, and Cochrane Library. Two reviewers will independently screen titles/abstracts and full-texts against eligibility criteria, extract the data, and assess the overall quality of evidence. Both observational and RCT studies will be eligible for inclusion if they report offspring mental health resilience/outcome and depressive symptoms or depressive disorder in at least one of the parents/caregivers. Risk of bias will be assessed using The Joanna Briggs Institute (JBI) critical appraisal checklists and The Revised Cochrane risk of bias tool for randomised trials (RoB 2). It is expected that studies will be heterogeneous; therefore, meta-analysis will not be attempted. Studies will be systematically retrieved and collated using numerical, graphical, tabular, and narrative summaries and grouped by their design, scope, or overall quality. Further sub-group analyses will be performed to examine sex-, developmental stage-, and outcome-specific protective factors. Discussion The proposed systematic review will be the first to summarise and critically assess quality and strength of evidence of protective factors associated with mental health resilience in offspring of depressed parents. Directions and effect sizes of the protective factors will be discussed as well as differences between the studies, their limitations, and research gaps and future directions. Strengths and limitations of the proposed systematic review will be also discussed. The proposed systematic review findings are expected to help better understand mental health resilience and identify targets for evidence-based prevention and intervention strategies for those in need. Systematic review registration A previous version of this systematic review protocol has been registered in the International Prospective Register of Systematic Reviews (PROSPERO) database ( www.crd.york.ac.uk/PROSPERO , CRD42021229955).
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spelling doaj.art-69860a29d810422981feee4bf51b5ae42022-12-22T03:12:59ZengBMCSystematic Reviews2046-40532022-09-011111810.1186/s13643-022-02056-6Mental health resilience in offspring of depressed parents: a systematic literature review protocolEglė Padaigaitė0Jessica Mayumi Maruyama1Gemma Hammerton2Frances Rice3Stephan Collishaw4Wolfson Centre for Young People’s Mental Health, Section of Child and Adolescent Psychiatry, Division of Psychological Medicine and Clinical Neurosciences, Cardiff UniversityDepartamento de Medicina Preventiva, Faculdade de Medicina FMUSP, Universidade de São PauloPopulation Health Sciences, Bristol Medical School, University of BristolWolfson Centre for Young People’s Mental Health, Section of Child and Adolescent Psychiatry, Division of Psychological Medicine and Clinical Neurosciences, Cardiff UniversityWolfson Centre for Young People’s Mental Health, Section of Child and Adolescent Psychiatry, Division of Psychological Medicine and Clinical Neurosciences, Cardiff UniversityAbstract Background Parental depression is associated with a range of mental health conditions and other difficulties in the offspring. Nevertheless, some offspring exposed to parental depression do not develop mental health problems, indicating the presence of protective factors that may buffer parental depression-related risk effects. However, evidence of protective factors that might explain good sustained mental health in offspring of depressed parents is limited and systematic synthesis of these factors is still needed. Therefore, as far as we are aware, this will be the first systematic review that will identify parent, family, child, social, and lifestyle factors associated with mental health resilience in offspring of depressed parents, examine evidence for sex-, developmental stage-, and outcome-specific factors and define mental health resilience in the parental depression context. Methods This protocol has been developed according to the PRISMA-P guidelines. Electronic searches will be performed for articles published up to 2022 in PsycINFO, Embase, MEDLINE, Web of Science Core Collection, and Cochrane Library. Two reviewers will independently screen titles/abstracts and full-texts against eligibility criteria, extract the data, and assess the overall quality of evidence. Both observational and RCT studies will be eligible for inclusion if they report offspring mental health resilience/outcome and depressive symptoms or depressive disorder in at least one of the parents/caregivers. Risk of bias will be assessed using The Joanna Briggs Institute (JBI) critical appraisal checklists and The Revised Cochrane risk of bias tool for randomised trials (RoB 2). It is expected that studies will be heterogeneous; therefore, meta-analysis will not be attempted. Studies will be systematically retrieved and collated using numerical, graphical, tabular, and narrative summaries and grouped by their design, scope, or overall quality. Further sub-group analyses will be performed to examine sex-, developmental stage-, and outcome-specific protective factors. Discussion The proposed systematic review will be the first to summarise and critically assess quality and strength of evidence of protective factors associated with mental health resilience in offspring of depressed parents. Directions and effect sizes of the protective factors will be discussed as well as differences between the studies, their limitations, and research gaps and future directions. Strengths and limitations of the proposed systematic review will be also discussed. The proposed systematic review findings are expected to help better understand mental health resilience and identify targets for evidence-based prevention and intervention strategies for those in need. Systematic review registration A previous version of this systematic review protocol has been registered in the International Prospective Register of Systematic Reviews (PROSPERO) database ( www.crd.york.ac.uk/PROSPERO , CRD42021229955).https://doi.org/10.1186/s13643-022-02056-6Mental HealthResilienceOffspringParentsDepressionSystematic review
spellingShingle Eglė Padaigaitė
Jessica Mayumi Maruyama
Gemma Hammerton
Frances Rice
Stephan Collishaw
Mental health resilience in offspring of depressed parents: a systematic literature review protocol
Systematic Reviews
Mental Health
Resilience
Offspring
Parents
Depression
Systematic review
title Mental health resilience in offspring of depressed parents: a systematic literature review protocol
title_full Mental health resilience in offspring of depressed parents: a systematic literature review protocol
title_fullStr Mental health resilience in offspring of depressed parents: a systematic literature review protocol
title_full_unstemmed Mental health resilience in offspring of depressed parents: a systematic literature review protocol
title_short Mental health resilience in offspring of depressed parents: a systematic literature review protocol
title_sort mental health resilience in offspring of depressed parents a systematic literature review protocol
topic Mental Health
Resilience
Offspring
Parents
Depression
Systematic review
url https://doi.org/10.1186/s13643-022-02056-6
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