<sup>68</sup>Ga-Pentixafor PET/CT May Fail to Detect Recurrent Multiple Myeloma with Extramedullary Disease
Two patients with a history of multiple myeloma experienced a recurrence of the disease.<sup>18</sup>F-FDG PET/CT revealed prominent extramedullary disease as well as multi-foci in the bone marrow, both with increased FDG uptake. However, on <sup>68</sup>Ga-Pentixafor PET/CT,...
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MDPI AG
2023-02-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/5/871 |
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| author | Qingqing Pan Yaping Luo Xinxin Cao Jian Li Fang Li |
| author_facet | Qingqing Pan Yaping Luo Xinxin Cao Jian Li Fang Li |
| author_sort | Qingqing Pan |
| collection | DOAJ |
| description | Two patients with a history of multiple myeloma experienced a recurrence of the disease.<sup>18</sup>F-FDG PET/CT revealed prominent extramedullary disease as well as multi-foci in the bone marrow, both with increased FDG uptake. However, on <sup>68</sup>Ga-Pentixafor PET/CT, all the myeloma lesions showed significantly lower tracer uptake in comparison with <sup>18</sup>F-FDG PET. This false-negative result of recurrent multiple myeloma with extramedullary disease may be a potential limitation of <sup>68</sup>Ga-Pentixafor in assessing multiple myeloma. |
| first_indexed | 2024-03-11T07:27:37Z |
| format | Article |
| id | doaj.art-698795d5dc634a7fbf0d9eac5c470f33 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T07:27:37Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-698795d5dc634a7fbf0d9eac5c470f332023-11-17T07:29:19ZengMDPI AGDiagnostics2075-44182023-02-0113587110.3390/diagnostics13050871<sup>68</sup>Ga-Pentixafor PET/CT May Fail to Detect Recurrent Multiple Myeloma with Extramedullary DiseaseQingqing Pan0Yaping Luo1Xinxin Cao2Jian Li3Fang Li4Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing 100730, ChinaDepartment of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing 100730, ChinaDepartment of Hematology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing 100730, ChinaDepartment of Hematology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing 100730, ChinaDepartment of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing 100730, ChinaTwo patients with a history of multiple myeloma experienced a recurrence of the disease.<sup>18</sup>F-FDG PET/CT revealed prominent extramedullary disease as well as multi-foci in the bone marrow, both with increased FDG uptake. However, on <sup>68</sup>Ga-Pentixafor PET/CT, all the myeloma lesions showed significantly lower tracer uptake in comparison with <sup>18</sup>F-FDG PET. This false-negative result of recurrent multiple myeloma with extramedullary disease may be a potential limitation of <sup>68</sup>Ga-Pentixafor in assessing multiple myeloma.https://www.mdpi.com/2075-4418/13/5/871multiple myelomaextramedullary disease<sup>68</sup>Ga-PentixaforPET/CT |
| spellingShingle | Qingqing Pan Yaping Luo Xinxin Cao Jian Li Fang Li <sup>68</sup>Ga-Pentixafor PET/CT May Fail to Detect Recurrent Multiple Myeloma with Extramedullary Disease Diagnostics multiple myeloma extramedullary disease <sup>68</sup>Ga-Pentixafor PET/CT |
| title | <sup>68</sup>Ga-Pentixafor PET/CT May Fail to Detect Recurrent Multiple Myeloma with Extramedullary Disease |
| title_full | <sup>68</sup>Ga-Pentixafor PET/CT May Fail to Detect Recurrent Multiple Myeloma with Extramedullary Disease |
| title_fullStr | <sup>68</sup>Ga-Pentixafor PET/CT May Fail to Detect Recurrent Multiple Myeloma with Extramedullary Disease |
| title_full_unstemmed | <sup>68</sup>Ga-Pentixafor PET/CT May Fail to Detect Recurrent Multiple Myeloma with Extramedullary Disease |
| title_short | <sup>68</sup>Ga-Pentixafor PET/CT May Fail to Detect Recurrent Multiple Myeloma with Extramedullary Disease |
| title_sort | sup 68 sup ga pentixafor pet ct may fail to detect recurrent multiple myeloma with extramedullary disease |
| topic | multiple myeloma extramedullary disease <sup>68</sup>Ga-Pentixafor PET/CT |
| url | https://www.mdpi.com/2075-4418/13/5/871 |
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