Effects of flaxseed supplementation on omega-6 to omega-3 fatty acid ratio, lipid mediator profile, proinflammatory cytokines and stress indices in laying hens
Although polyunsaturated fatty acids (PUFAs) have gained attention because of their physiological effects on inflammation and stress, their derivatives, termed lipid mediators, have been rarely examined, especially in laying hens. In this study, we aimed to investigate PUFA and lipid mediator profil...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-01-01
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| Series: | Journal of Applied Animal Research |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09712119.2021.2000416 |
| _version_ | 1798022580880277504 |
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| author | Sang-Mok Lee Hee Kyum Kim Ho-Bin Lee Oh-Dae Kwon Eun-Bi Lee Jin-Duck Bok Chong-Su Cho Yun-Jaie Choi Sang-Kee Kang |
| author_facet | Sang-Mok Lee Hee Kyum Kim Ho-Bin Lee Oh-Dae Kwon Eun-Bi Lee Jin-Duck Bok Chong-Su Cho Yun-Jaie Choi Sang-Kee Kang |
| author_sort | Sang-Mok Lee |
| collection | DOAJ |
| description | Although polyunsaturated fatty acids (PUFAs) have gained attention because of their physiological effects on inflammation and stress, their derivatives, termed lipid mediators, have been rarely examined, especially in laying hens. In this study, we aimed to investigate PUFA and lipid mediator profiles of laying hens after feeding 0, 0.9, 1.8, or 3.6% (w/w) dietary flaxseed (Lintex170) for 4 weeks. We also monitored the indices of inflammation (serum proinflammatory cytokines) and stress (serum corticosterone, ratio of heterophils to lymphocytes). In this study, flaxseed reduced the omega-6 to omega-3 FA ratio and increased several omega-3 FA-derived lipid mediators. Furthermore, levels of the proinflammatory cytokine tumour necrosis factor alpha and two stress indices (corticosterone, heterophil to lymphocyte ratio) were decreased when fed the 3.6% flaxseed diet. Overall, laying performance indices were also significantly improved by flaxseed treatment. These findings suggest that flaxseed may alleviate the stress state of laying hens by enriching omega-3-derived lipid mediators, which could improve laying performance. |
| first_indexed | 2024-04-11T17:33:25Z |
| format | Article |
| id | doaj.art-6987d19d2e554576af7549a873d8cb8b |
| institution | Directory Open Access Journal |
| issn | 0971-2119 0974-1844 |
| language | English |
| last_indexed | 2024-04-11T17:33:25Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Applied Animal Research |
| spelling | doaj.art-6987d19d2e554576af7549a873d8cb8b2022-12-22T04:11:57ZengTaylor & Francis GroupJournal of Applied Animal Research0971-21190974-18442021-01-0149146047110.1080/09712119.2021.20004162000416Effects of flaxseed supplementation on omega-6 to omega-3 fatty acid ratio, lipid mediator profile, proinflammatory cytokines and stress indices in laying hensSang-Mok Lee0Hee Kyum Kim1Ho-Bin Lee2Oh-Dae Kwon3Eun-Bi Lee4Jin-Duck Bok5Chong-Su Cho6Yun-Jaie Choi7Sang-Kee Kang8Seoul National UniversitySeoul National UniversityInstitute of Green-Bio Science & Technology, Seoul National UniversityInstitute of Green-Bio Science & Technology, Seoul National UniversityInstitute of Green-Bio Science & Technology, Seoul National UniversityInstitute of Green-Bio Science & Technology, Seoul National UniversitySeoul National UniversitySeoul National UniversityInstitute of Green-Bio Science & Technology, Seoul National UniversityAlthough polyunsaturated fatty acids (PUFAs) have gained attention because of their physiological effects on inflammation and stress, their derivatives, termed lipid mediators, have been rarely examined, especially in laying hens. In this study, we aimed to investigate PUFA and lipid mediator profiles of laying hens after feeding 0, 0.9, 1.8, or 3.6% (w/w) dietary flaxseed (Lintex170) for 4 weeks. We also monitored the indices of inflammation (serum proinflammatory cytokines) and stress (serum corticosterone, ratio of heterophils to lymphocytes). In this study, flaxseed reduced the omega-6 to omega-3 FA ratio and increased several omega-3 FA-derived lipid mediators. Furthermore, levels of the proinflammatory cytokine tumour necrosis factor alpha and two stress indices (corticosterone, heterophil to lymphocyte ratio) were decreased when fed the 3.6% flaxseed diet. Overall, laying performance indices were also significantly improved by flaxseed treatment. These findings suggest that flaxseed may alleviate the stress state of laying hens by enriching omega-3-derived lipid mediators, which could improve laying performance.http://dx.doi.org/10.1080/09712119.2021.2000416flaxseedinflammationlipid mediatoromega-6 to omega-3 fatty acid balancepolyunsaturated fatty acidstress |
| spellingShingle | Sang-Mok Lee Hee Kyum Kim Ho-Bin Lee Oh-Dae Kwon Eun-Bi Lee Jin-Duck Bok Chong-Su Cho Yun-Jaie Choi Sang-Kee Kang Effects of flaxseed supplementation on omega-6 to omega-3 fatty acid ratio, lipid mediator profile, proinflammatory cytokines and stress indices in laying hens Journal of Applied Animal Research flaxseed inflammation lipid mediator omega-6 to omega-3 fatty acid balance polyunsaturated fatty acid stress |
| title | Effects of flaxseed supplementation on omega-6 to omega-3 fatty acid ratio, lipid mediator profile, proinflammatory cytokines and stress indices in laying hens |
| title_full | Effects of flaxseed supplementation on omega-6 to omega-3 fatty acid ratio, lipid mediator profile, proinflammatory cytokines and stress indices in laying hens |
| title_fullStr | Effects of flaxseed supplementation on omega-6 to omega-3 fatty acid ratio, lipid mediator profile, proinflammatory cytokines and stress indices in laying hens |
| title_full_unstemmed | Effects of flaxseed supplementation on omega-6 to omega-3 fatty acid ratio, lipid mediator profile, proinflammatory cytokines and stress indices in laying hens |
| title_short | Effects of flaxseed supplementation on omega-6 to omega-3 fatty acid ratio, lipid mediator profile, proinflammatory cytokines and stress indices in laying hens |
| title_sort | effects of flaxseed supplementation on omega 6 to omega 3 fatty acid ratio lipid mediator profile proinflammatory cytokines and stress indices in laying hens |
| topic | flaxseed inflammation lipid mediator omega-6 to omega-3 fatty acid balance polyunsaturated fatty acid stress |
| url | http://dx.doi.org/10.1080/09712119.2021.2000416 |
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