New approach to heart rate control as mortality reduction method in cardiac patients: potential of a new If inhibitor, ivabradine

New approach to heart rate control as mortality reduction method in cardiac patients: potential of a new If inhibitor, ivabradine

Large-scale epidemiological studies have demonstrated that heart rate (HR) is an independent risk factor, increasing total, sudden and cardiovascular mortality risk. Ivabradine specifically binds to sinus node (SN) f-channels and reduces HR. Due to its specific SN action and selective If current inh...

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Bibliographic Details
Main Authors: Yu. B. Belousov, O. A. Maneshina, S. B. Erofeeva
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2007-12-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
частота сердечных сокращений
сердечно-сосудистая смертность
ишемическая болезнь сердца
стабильная стенокардия
f-каналы
ионные токи if
ивабрадин
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1417

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