Complexation and enhancement of temozolomide solubility with cyclodextrins

Complexation and enhancement of temozolomide solubility with cyclodextrins

ABSTRACT Temozolomide is a poorly soluble anti-cancer drug used in the treatment of some brain cancers. Following literature reports about the enhancement of solubility and stability for these kinds of drugs upon complexation with cyclodextrins, we aimed to form an inclusion complex between temozolo...

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Bibliographic Details
Main Authors:	Berna Gürten, Elçin Yenigül, Ali Demir Sezer, Seyda Malta
Format:	Article
Language:	English
Published:	Universidade de São Paulo 2018-07-01
Series:	Brazilian Journal of Pharmaceutical Sciences
Subjects:	Temozolomide/solubility/complexation Cyclodextrins Chromatography Calorimetry.
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000200606&lng=en&tlng=en

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