Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury
The dynamics of fibroadipogenic progenitors (FAPs) after muscle injury are crucial to ensure efficient regeneration. Here the authors show that a pool of FAPs originates from adipose tissue and are necessary for effective muscle regeneration.
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-35524-7 |
| _version_ | 1797853719842258944 |
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| author | Quentin Sastourné-Arrey Maxime Mathieu Xavier Contreras Sylvie Monferran Virginie Bourlier Marta Gil-Ortega Enda Murphy Claire Laurens Audrey Varin Christophe Guissard Corinne Barreau Mireille André Noémie Juin Marie Marquès Benoit Chaput Cédric Moro Donal O’Gorman Louis Casteilla Amandine Girousse Coralie Sengenès |
| author_facet | Quentin Sastourné-Arrey Maxime Mathieu Xavier Contreras Sylvie Monferran Virginie Bourlier Marta Gil-Ortega Enda Murphy Claire Laurens Audrey Varin Christophe Guissard Corinne Barreau Mireille André Noémie Juin Marie Marquès Benoit Chaput Cédric Moro Donal O’Gorman Louis Casteilla Amandine Girousse Coralie Sengenès |
| author_sort | Quentin Sastourné-Arrey |
| collection | DOAJ |
| description | The dynamics of fibroadipogenic progenitors (FAPs) after muscle injury are crucial to ensure efficient regeneration. Here the authors show that a pool of FAPs originates from adipose tissue and are necessary for effective muscle regeneration. |
| first_indexed | 2024-04-09T19:54:11Z |
| format | Article |
| id | doaj.art-698c21125fc94f9fad23509d7242420d |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-09T19:54:11Z |
| publishDate | 2023-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-698c21125fc94f9fad23509d7242420d2023-04-03T05:33:23ZengNature PortfolioNature Communications2041-17232023-01-0114111710.1038/s41467-022-35524-7Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injuryQuentin Sastourné-Arrey0Maxime Mathieu1Xavier Contreras2Sylvie Monferran3Virginie Bourlier4Marta Gil-Ortega5Enda Murphy6Claire Laurens7Audrey Varin8Christophe Guissard9Corinne Barreau10Mireille André11Noémie Juin12Marie Marquès13Benoit Chaput14Cédric Moro15Donal O’Gorman16Louis Casteilla17Amandine Girousse18Coralie Sengenès19RESTORE, Research Center, Team 1 STROMAGICS, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierRESTORE, Research Center, Team 1 STROMAGICS, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierRESTORE, Research Center, Team 1 STROMAGICS, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierRESTORE, Research Center, Team 1 STROMAGICS, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierInstitute of Metabolic and Cardiovascular Diseases, INSERM /Paul Sabatier University UMR 1297, Team MetaDiabRESTORE, Research Center, Team 1 STROMAGICS, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierSchool of Health and Human Performance, Dublin City UniversityInstitute of Metabolic and Cardiovascular Diseases, INSERM /Paul Sabatier University UMR 1297, Team MetaDiabRESTORE, Research Center, Team 2 FLAMES, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierRESTORE, Research Center, Team 4 GOT-IT, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierRESTORE, Research Center, Team 1 STROMAGICS, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierRESTORE, Research Center, Team 1 STROMAGICS, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierRESTORE, Research Center, Team 1 STROMAGICS, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierInstitute of Metabolic and Cardiovascular Diseases, INSERM /Paul Sabatier University UMR 1297, Team MetaDiabDepartment of Plastic and Reconstructive Surgery, Toulouse University HospitalInstitute of Metabolic and Cardiovascular Diseases, INSERM /Paul Sabatier University UMR 1297, Team MetaDiabSchool of Health and Human Performance, Dublin City UniversityRESTORE, Research Center, Team 4 GOT-IT, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierRESTORE, Research Center, Team 1 STROMAGICS, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierRESTORE, Research Center, Team 1 STROMAGICS, Université de Toulouse, INSERM, CNRS, EFS, ENVT, Université P. SabatierThe dynamics of fibroadipogenic progenitors (FAPs) after muscle injury are crucial to ensure efficient regeneration. Here the authors show that a pool of FAPs originates from adipose tissue and are necessary for effective muscle regeneration.https://doi.org/10.1038/s41467-022-35524-7 |
| spellingShingle | Quentin Sastourné-Arrey Maxime Mathieu Xavier Contreras Sylvie Monferran Virginie Bourlier Marta Gil-Ortega Enda Murphy Claire Laurens Audrey Varin Christophe Guissard Corinne Barreau Mireille André Noémie Juin Marie Marquès Benoit Chaput Cédric Moro Donal O’Gorman Louis Casteilla Amandine Girousse Coralie Sengenès Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury Nature Communications |
| title | Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury |
| title_full | Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury |
| title_fullStr | Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury |
| title_full_unstemmed | Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury |
| title_short | Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury |
| title_sort | adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury |
| url | https://doi.org/10.1038/s41467-022-35524-7 |
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