Fitness for Entering a Simple Exercise Program and Mortality: A Study Corollary to the Exercise Introduction to Enhance Performance in Dialysis (Excite) Trial

Fitness for Entering a Simple Exercise Program and Mortality: A Study Corollary to the Exercise Introduction to Enhance Performance in Dialysis (Excite) Trial

Background/Aims: In this corollary analysis of the EXCITE study, we looked at possible differences in baseline risk factors and mortality between subjects excluded from the trial because non-eligible (n=216) or because eligible but refusing to participate (n=116). Methods: Baseline characteristics a...

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Bibliographic Details
Main Authors: Rossella Baggetta, Davide Bolignano, Claudia Torino, Fabio Manfredini, Filippo Aucella, Antonio Barillà, Yuri Battaglia, Silvio Bertoli, Graziella Bonanno, Pietro Castellino, Daniele Ciurlino, Adamasco Cupisti, Graziella D'Arrigo, Luciano De Paola, Fabrizio Fabrizi, Pasquale Fatuzzo, Giorgio Fuiano, Luigi Lombardi, Gaetano Lucisano, Piergiorgio Messa, Renato Rapanà, Francesco Rapisarda, Stefania Rastelli, Lisa Rocca-Rey, Chiara Summaria, Alessandro Zuccalà, Samar Abd ElHafeez, Giovanni Tripepi, Luigi Catizone, Francesca Mallamaci, Carmine Zoccali
Format: Article
Language:English
Published: Karger Publishers 2014-07-01
Series:Kidney & Blood Pressure Research
Subjects:
Dialysis
Deambulation
Physical exercise
Mortality
Outcome study
Online Access:http://www.karger.com/Article/FullText/355797
Description
Summary:Background/Aims: In this corollary analysis of the EXCITE study, we looked at possible differences in baseline risk factors and mortality between subjects excluded from the trial because non-eligible (n=216) or because eligible but refusing to participate (n=116). Methods: Baseline characteristics and mortality data were recorded. Survival and independent predictors of mortality were assessed by Kaplan-Meier and Cox regression analyses. Results: The incidence rate of mortality was higher in non-eligible vs. eligible non-randomized patients (21.0 vs. 10.9 deaths/100 persons-year; PConclusions: Deambulation ability mostly explains the difference in survival rate in non-eligible and eligible non-randomized patients in the EXCITE trial. Extending data analyses and outcome reporting also to subjects not taking part in a trial may be helpful to assess the representability of the study population.
ISSN:1420-4096
1423-0143

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