Immunization with recombinant Nogo-66 receptor (NgR) promotes axonal regeneration and recovery of function after spinal cord injury in rats

Immunization with recombinant Nogo-66 receptor (NgR) promotes axonal regeneration and recovery of function after spinal cord injury in rats

Nogo-66 receptor (NgR), a common receptor for the three known myelin-associated inhibitors, i.e., Nogo-A, myelin-associated glycoprotein (MAG), and oligodendrocyte myelin glycoprotein (OMgp), plays a key role in the failure of axonal regeneration in the adult mammalian central nervous system (CNS)....

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Bibliographic Details
Main Authors: Panpan Yu, Lidong Huang, Jian Zou, Zhihua Yu, Yanxia Wang, Xiaofei Wang, Liang Xu, Xinqiu Liu, Xiao-Ming Xu, Pei-Hua Lu
Format: Article
Language:English
Published: Elsevier 2008-12-01
Series:Neurobiology of Disease
Subjects:
NgR
Vaccine
Spinal cord injury
Axon regeneration
Functional recovery
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108002209

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