Dysregulated CREB3 cleavage at the nuclear membrane induces karyoptosis-mediated cell death
Abstract Cancer cells often exhibit resistance to apoptotic cell death, but they may be vulnerable to other types of cell death. Elucidating additional mechanisms that govern cancer cell death is crucial for developing new therapies. Our research identified cyclic AMP-responsive element-binding prot...
Main Authors: | Ga-Eun Lee, Geul Bang, Jiin Byun, Cheol-Jung Lee, Weidong Chen, Dohyun Jeung, Hyun-Jung An, Han Chang Kang, Joo Young Lee, Hye Suk Lee, Young-Soo Hong, Dae Joon Kim, Megan Keniry, Jin Young Kim, Jin-Sung Choi, Manolis Fanto, Sung-Jun Cho, Kwang-Dong Kim, Yong-Yeon Cho |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2024-03-01
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Series: | Experimental and Molecular Medicine |
Online Access: | https://doi.org/10.1038/s12276-024-01195-1 |
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