Mitochondrial Targeting of the Enteropathogenic <named-content content-type="genus-species">Escherichia coli</named-content> Map Triggers Calcium Mobilization, ADAM10-MAP Kinase Signaling, and Host Cell Apoptosis

Mitochondrial Targeting of the Enteropathogenic <named-content content-type="genus-species">Escherichia coli</named-content> Map Triggers Calcium Mobilization, ADAM10-MAP Kinase Signaling, and Host Cell Apoptosis

ABSTRACT The ability of diarrheagenic bacterial pathogens, such as enteropathogenic Escherichia coli (EPEC), to modulate the activity of mitogen-activated protein kinases (MAPKs) and cell survival has been suggested to benefit bacterial colonization and infection. However, our understanding of the m...

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Bibliographic Details
Main Authors: Rachana Pattani Ramachandran, Chaya Spiegel, Yael Keren, Tsafi Danieli, Naomi Melamed-Book, Ritesh Ranjan Pal, Efrat Zlotkin-Rivkin, Ilan Rosenshine, Benjamin Aroeti
Format: Article
Language:English
Published: American Society for Microbiology 2020-10-01
Series:mBio
Subjects:
ADAM10
calcium
enteropathogenic E. coli
MAP kinases
Map effector
protein effectors
Online Access:https://journals.asm.org/doi/10.1128/mBio.01397-20

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