The Association between Endometriosis and Obstructive Müllerian Anomalies
It is unclear whether clinical background differs between endometriosis in adolescent patients with obstructive Müllerian anomalies and those without anomalies. The aim of the study is to identify the difference in clinical characteristics of endometriosis in patients with or without obstructive Mül...
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MDPI AG
2024-03-01
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| author | Nozomi Takahashi Miyuki Harada Mayuko Kanatani Osamu Wada-Hiraike Yasushi Hirota Yutaka Osuga |
| author_facet | Nozomi Takahashi Miyuki Harada Mayuko Kanatani Osamu Wada-Hiraike Yasushi Hirota Yutaka Osuga |
| author_sort | Nozomi Takahashi |
| collection | DOAJ |
| description | It is unclear whether clinical background differs between endometriosis in adolescent patients with obstructive Müllerian anomalies and those without anomalies. The aim of the study is to identify the difference in clinical characteristics of endometriosis in patients with or without obstructive Müllerian anomalies. The study involved 12 patients aged under 24 years old who underwent primary surgery for obstructive Müllerian anomalies and 31 patients aged under 24 years old who underwent surgery for ovarian endometrioma. A total of 6 out of 12 cases with obstructive Müllerian anomalies developed endometriosis (4 Herlyn–Werner–Wunderlich syndrome, 2 non-communicating functional uterine horn, 2 cervical aplasia). The age at surgery was significantly younger in endometriosis with obstructive Müllerian anomalies, compared with those without obstructive Müllerian anomalies (17.8 ± 4.4 vs. 23.1 ± 1.3, <i>p</i> = 0.0007). The rate of endometrioma was 50.0% and the rate of hydrosalpinx was significantly higher (66.7% vs. 0%, <i>p</i> = 0.0002) in the group of obstructive Müllerian anomalies. The recurrence rate of endometriosis was 20.0% in the group of anomalies and 25.9% in the group of those without anomalies. Adolescent patients with obstructive Müllerian anomalies more easily developed endometriosis and co-occurred with higher rate of hematosalipinx. |
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| last_indexed | 2024-04-24T18:31:13Z |
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| spelling | doaj.art-699c7a64b6664c22b09803d282bbdb732024-03-27T13:23:02ZengMDPI AGBiomedicines2227-90592024-03-0112365110.3390/biomedicines12030651The Association between Endometriosis and Obstructive Müllerian AnomaliesNozomi Takahashi0Miyuki Harada1Mayuko Kanatani2Osamu Wada-Hiraike3Yasushi Hirota4Yutaka Osuga5Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo 113-8655, JapanDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo 113-8655, JapanDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo 113-8655, JapanDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo 113-8655, JapanDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo 113-8655, JapanDepartment of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo 113-8655, JapanIt is unclear whether clinical background differs between endometriosis in adolescent patients with obstructive Müllerian anomalies and those without anomalies. The aim of the study is to identify the difference in clinical characteristics of endometriosis in patients with or without obstructive Müllerian anomalies. The study involved 12 patients aged under 24 years old who underwent primary surgery for obstructive Müllerian anomalies and 31 patients aged under 24 years old who underwent surgery for ovarian endometrioma. A total of 6 out of 12 cases with obstructive Müllerian anomalies developed endometriosis (4 Herlyn–Werner–Wunderlich syndrome, 2 non-communicating functional uterine horn, 2 cervical aplasia). The age at surgery was significantly younger in endometriosis with obstructive Müllerian anomalies, compared with those without obstructive Müllerian anomalies (17.8 ± 4.4 vs. 23.1 ± 1.3, <i>p</i> = 0.0007). The rate of endometrioma was 50.0% and the rate of hydrosalpinx was significantly higher (66.7% vs. 0%, <i>p</i> = 0.0002) in the group of obstructive Müllerian anomalies. The recurrence rate of endometriosis was 20.0% in the group of anomalies and 25.9% in the group of those without anomalies. Adolescent patients with obstructive Müllerian anomalies more easily developed endometriosis and co-occurred with higher rate of hematosalipinx.https://www.mdpi.com/2227-9059/12/3/651cervical aplasiadysmenorrheaendometriosisHerlyn–Werner–Wunderlich syndromeMüllerian anomalies |
| spellingShingle | Nozomi Takahashi Miyuki Harada Mayuko Kanatani Osamu Wada-Hiraike Yasushi Hirota Yutaka Osuga The Association between Endometriosis and Obstructive Müllerian Anomalies Biomedicines cervical aplasia dysmenorrhea endometriosis Herlyn–Werner–Wunderlich syndrome Müllerian anomalies |
| title | The Association between Endometriosis and Obstructive Müllerian Anomalies |
| title_full | The Association between Endometriosis and Obstructive Müllerian Anomalies |
| title_fullStr | The Association between Endometriosis and Obstructive Müllerian Anomalies |
| title_full_unstemmed | The Association between Endometriosis and Obstructive Müllerian Anomalies |
| title_short | The Association between Endometriosis and Obstructive Müllerian Anomalies |
| title_sort | association between endometriosis and obstructive mullerian anomalies |
| topic | cervical aplasia dysmenorrhea endometriosis Herlyn–Werner–Wunderlich syndrome Müllerian anomalies |
| url | https://www.mdpi.com/2227-9059/12/3/651 |
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