The haemostatic effect of deep-frozen platelets versus room temperature-stored platelets in the treatment of surgical bleeding: MAFOD—study protocol for a randomized controlled non-inferiority trial

The haemostatic effect of deep-frozen platelets versus room temperature-stored platelets in the treatment of surgical bleeding: MAFOD—study protocol for a randomized controlled non-inferiority trial

Abstract Background The Netherlands Armed Forces have been successfully using deep-frozen (− 80 °C) thrombocyte concentrate (DTC) for the treatment of (massive) bleeding trauma patients in austere environments since 2001. However, high-quality evidence for the effectiveness and safety of DTCs is cur...

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Bibliographic Details
Main Authors: Tim W. H. Rijnhout, Femke Noorman, Robert A. van der Horst, Edward C. T. H. Tan, Victor V. A. Viersen, Oscar J. F. van Waes, Leo M. G. van de Watering, B. L. S. Borger van der Burg, Jaap J. Zwaginga, Michael H. J. Verhofstad, Rigo Hoencamp
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Trials
Subjects:
Transfusion
Cryopreservation
Trauma
Bleeding
Haemorrhage
Platelets
Online Access:https://doi.org/10.1186/s13063-022-06739-2

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