Use of metabolites, metabolithotropic agents and nutritional supplements in sports and sports medicine: a modern view on the problem

Aim. The purpose of this study was to conduct an up-to-date semantic analysis of the results of our own research and literature data on the medical and pharmacological characteristics of metabolites, metabolitotropic agents and nutritional supplements, the peculiarities of their use in sports practi...

Full description

Bibliographic Details
Main Authors: I. F. Bielenichev, N. A. Gorchakova, E. Yu. Doroshenko, I. B. Samura, V. P. Ryzhenko, N. V. Bukhtiiarova
Format: Article
Language:English
Published: Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine 2023-12-01
Series:Сучасні медичні технології
Subjects:
Online Access:https://zmapo-journal.com/index.php/journal/article/view/300
_version_ 1797401215250726912
author I. F. Bielenichev
N. A. Gorchakova
E. Yu. Doroshenko
I. B. Samura
V. P. Ryzhenko
N. V. Bukhtiiarova
author_facet I. F. Bielenichev
N. A. Gorchakova
E. Yu. Doroshenko
I. B. Samura
V. P. Ryzhenko
N. V. Bukhtiiarova
author_sort I. F. Bielenichev
collection DOAJ
description Aim. The purpose of this study was to conduct an up-to-date semantic analysis of the results of our own research and literature data on the medical and pharmacological characteristics of metabolites, metabolitotropic agents and nutritional supplements, the peculiarities of their use in sports practice and sports medicine. Materials and methods. This study used bibliosemantic, analytical, logical, and generalization methods. The life sciences and biomedical information bibliographic databases MEDLINE, EMBASE, Medline (PubMed), Web of Science, and Cochrane Central were searched to find publications in English that matched the research keywords. The authors carried out an independent search and selection of articles, assessment of the quality of the data, compliance of the presentation and interpretation with the main idea of the study, with the formation of the final list of references. Results. Based on the analysis of modern literature data and the results of our own studies, a generalized medical and pharmacological characteristic of metabolite agents, metabolitotropic drugs and nutritional supplements that can influence the main and compensatory mechanisms of macroergic phosphates production under the influence of physical activity is presented. The mechanisms of action, indications for use and main side effects of drugs and food additives based on ATP, malate, succinate, citrate, pyruvate, carnitine, carnosine, etc. are presented. Conclusions. Semantic analysis data indicate that an urgent problem for sports medicine physicians and pharmacologists is the development and use of metabolites, metabolitotropic agents and nutritional supplements, as well as approaches to their rational combination to improve energy metabolism, replenish ATP reserves in the body that will help ensure the intensity muscular activity and simultaneously protect target organs.
first_indexed 2024-03-09T02:06:38Z
format Article
id doaj.art-69a3332ff0e14b1a9a32108f97022374
institution Directory Open Access Journal
issn 2072-9367
language English
last_indexed 2024-03-09T02:06:38Z
publishDate 2023-12-01
publisher Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine
record_format Article
series Сучасні медичні технології
spelling doaj.art-69a3332ff0e14b1a9a32108f970223742023-12-07T16:14:45ZengZaporizhia Medical Academy of Post-Graduate Education Ministry of Health of UkraineСучасні медичні технології2072-93672023-12-014768810.34287/MMT.4(59).2023.10300Use of metabolites, metabolithotropic agents and nutritional supplements in sports and sports medicine: a modern view on the problemI. F. Bielenichev0N. A. Gorchakova1E. Yu. Doroshenko2I. B. Samura3V. P. Ryzhenko4N. V. Bukhtiiarova5Zaporizhzhia State Medical and Pharmaceutical University, UkraineBogomolets National Medical University, Kyiv, UkraineZaporizhzhia State Medical and Pharmaceutical University, UkraineZaporizhzhia State Medical and Pharmaceutical University, UkraineZaporizhzhia State Medical and Pharmaceutical University, UkraineZaporizhzhia State Medical and Pharmaceutical University, UkraineAim. The purpose of this study was to conduct an up-to-date semantic analysis of the results of our own research and literature data on the medical and pharmacological characteristics of metabolites, metabolitotropic agents and nutritional supplements, the peculiarities of their use in sports practice and sports medicine. Materials and methods. This study used bibliosemantic, analytical, logical, and generalization methods. The life sciences and biomedical information bibliographic databases MEDLINE, EMBASE, Medline (PubMed), Web of Science, and Cochrane Central were searched to find publications in English that matched the research keywords. The authors carried out an independent search and selection of articles, assessment of the quality of the data, compliance of the presentation and interpretation with the main idea of the study, with the formation of the final list of references. Results. Based on the analysis of modern literature data and the results of our own studies, a generalized medical and pharmacological characteristic of metabolite agents, metabolitotropic drugs and nutritional supplements that can influence the main and compensatory mechanisms of macroergic phosphates production under the influence of physical activity is presented. The mechanisms of action, indications for use and main side effects of drugs and food additives based on ATP, malate, succinate, citrate, pyruvate, carnitine, carnosine, etc. are presented. Conclusions. Semantic analysis data indicate that an urgent problem for sports medicine physicians and pharmacologists is the development and use of metabolites, metabolitotropic agents and nutritional supplements, as well as approaches to their rational combination to improve energy metabolism, replenish ATP reserves in the body that will help ensure the intensity muscular activity and simultaneously protect target organs.https://zmapo-journal.com/index.php/journal/article/view/300sportssport trainingmetabolite agentsmetabolitotropic drugsnutritional supplements
spellingShingle I. F. Bielenichev
N. A. Gorchakova
E. Yu. Doroshenko
I. B. Samura
V. P. Ryzhenko
N. V. Bukhtiiarova
Use of metabolites, metabolithotropic agents and nutritional supplements in sports and sports medicine: a modern view on the problem
Сучасні медичні технології
sports
sport training
metabolite agents
metabolitotropic drugs
nutritional supplements
title Use of metabolites, metabolithotropic agents and nutritional supplements in sports and sports medicine: a modern view on the problem
title_full Use of metabolites, metabolithotropic agents and nutritional supplements in sports and sports medicine: a modern view on the problem
title_fullStr Use of metabolites, metabolithotropic agents and nutritional supplements in sports and sports medicine: a modern view on the problem
title_full_unstemmed Use of metabolites, metabolithotropic agents and nutritional supplements in sports and sports medicine: a modern view on the problem
title_short Use of metabolites, metabolithotropic agents and nutritional supplements in sports and sports medicine: a modern view on the problem
title_sort use of metabolites metabolithotropic agents and nutritional supplements in sports and sports medicine a modern view on the problem
topic sports
sport training
metabolite agents
metabolitotropic drugs
nutritional supplements
url https://zmapo-journal.com/index.php/journal/article/view/300
work_keys_str_mv AT ifbielenichev useofmetabolitesmetabolithotropicagentsandnutritionalsupplementsinsportsandsportsmedicineamodernviewontheproblem
AT nagorchakova useofmetabolitesmetabolithotropicagentsandnutritionalsupplementsinsportsandsportsmedicineamodernviewontheproblem
AT eyudoroshenko useofmetabolitesmetabolithotropicagentsandnutritionalsupplementsinsportsandsportsmedicineamodernviewontheproblem
AT ibsamura useofmetabolitesmetabolithotropicagentsandnutritionalsupplementsinsportsandsportsmedicineamodernviewontheproblem
AT vpryzhenko useofmetabolitesmetabolithotropicagentsandnutritionalsupplementsinsportsandsportsmedicineamodernviewontheproblem
AT nvbukhtiiarova useofmetabolitesmetabolithotropicagentsandnutritionalsupplementsinsportsandsportsmedicineamodernviewontheproblem