Nucleotide Excision Repair Pathway Activity Is Inhibited by Airborne Particulate Matter (PM<sub>10</sub>) through XPA Deregulation in Lung Epithelial Cells

Nucleotide Excision Repair Pathway Activity Is Inhibited by Airborne Particulate Matter (PM<sub>10</sub>) through XPA Deregulation in Lung Epithelial Cells

Airborne particulate matter with a diameter size of ≤10 µm (PM<sub>10</sub>) is a carcinogen that contains polycyclic aromatic hydrocarbons (PAH), which form PAH–DNA adducts. However, the way in which these adducts are managed by DNA repair pathways in cells exposed to PM<sub>10<...

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Bibliographic Details
Main Authors: Ericka Marel Quezada-Maldonado, Yolanda I. Chirino, María Eugenia Gonsebatt, Rocío Morales-Bárcenas, Yesennia Sánchez-Pérez, Claudia M. García-Cuellar
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
DNA adducts
DNA repair inhibition
nucleotide excision repair pathway
particulate matter
lung cancer
Online Access:https://www.mdpi.com/1422-0067/23/4/2224

Internet

https://www.mdpi.com/1422-0067/23/4/2224

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