Comparative analysis of acoustic therapies for tinnitus treatment based on auditory event-related potentials
IntroductionSo far, Auditory Event-Related Potential (AERP) features have been used to characterize neural activity of patients with tinnitus. However, these EEG patterns could be used to evaluate tinnitus evolution as well. The aim of the present study is to propose a methodology based on AERPs to...
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2023.1059096/full |
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| author | Luz M. Alonso-Valerdi David I. Ibarra-Zárate Alma S. Torres-Torres Daniela M. Zolezzi Norberto E. Naal-Ruiz Janet Argüello-García |
| author_facet | Luz M. Alonso-Valerdi David I. Ibarra-Zárate Alma S. Torres-Torres Daniela M. Zolezzi Norberto E. Naal-Ruiz Janet Argüello-García |
| author_sort | Luz M. Alonso-Valerdi |
| collection | DOAJ |
| description | IntroductionSo far, Auditory Event-Related Potential (AERP) features have been used to characterize neural activity of patients with tinnitus. However, these EEG patterns could be used to evaluate tinnitus evolution as well. The aim of the present study is to propose a methodology based on AERPs to evaluate the effectiveness of four acoustic therapies for tinnitus treatment.MethodsThe acoustic therapies were: (1) Tinnitus Retraining Therapy (TRT), (2) Auditory Discrimination Therapy (ADT), (3) Therapy for Enriched Acoustic Environment (TEAE), and (4) Binaural Beats Therapy (BBT). In addition, relaxing music was included as a placebo for both: tinnitus sufferers and healthy individuals. To meet this aim, 103 participants were recruited, 53% were females and 47% were males. All the participants were treated for 8 weeks with one of these five sounds, which were moreover tuned in accordance with the acoustic features of their tinnitus (if applied) and hearing loss. They were electroencephalographically monitored before and after their acoustic therapy, and wherefrom AERPs were estimated. The sound effect of acoustic therapies was evaluated by examining the area under the curve of those AERPs. Two parameters were obtained: (1) amplitude and (2) topographical distribution.ResultsThe findings of the investigation showed that after an 8-week treatment, TRT and ADT, respectively achieved significant neurophysiological changes over somatosensory and occipital regions. On one hand, TRT increased the tinnitus perception. On the other hand, ADT redirected the tinnitus attention, what in turn diminished the tinnitus perception. Tinnitus handicapped inventory outcomes verified these neurophysiological findings, revealing that 31% of patients in each group reported that TRT increased tinnitus perception, but ADT diminished it.DiscussionTinnitus has been identified as a multifactorial condition highly associated with hearing loss, age, sex, marital status, education, and even, employment. However, no conclusive evidence has been found yet. In this study, a significant (but low) correlation was found between tinnitus intensity and right ear hearing loss, left ear hearing loss, heart rate, area under the curve of AERPs, and acoustic therapy. This study raises the possibility to assign acoustic therapies by neurophysiological response of patient. |
| first_indexed | 2024-04-09T19:41:03Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-04-09T19:41:03Z |
| publishDate | 2023-04-01 |
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| series | Frontiers in Neuroscience |
| spelling | doaj.art-69a576985fe441fda54b9cf617159d2e2023-04-04T05:51:44ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2023-04-011710.3389/fnins.2023.10590961059096Comparative analysis of acoustic therapies for tinnitus treatment based on auditory event-related potentialsLuz M. Alonso-Valerdi0David I. Ibarra-Zárate1Alma S. Torres-Torres2Daniela M. Zolezzi3Norberto E. Naal-Ruiz4Janet Argüello-García5Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Monterrey, MexicoTecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Monterrey, MexicoTecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Monterrey, MexicoTecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Monterrey, MexicoTecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Monterrey, MexicoUnidad Profesional Interdisciplinaria en Ingeniería y Tecnologías Avanzadas, Instituto Politécnico Nacional, Mexico City, MexicoIntroductionSo far, Auditory Event-Related Potential (AERP) features have been used to characterize neural activity of patients with tinnitus. However, these EEG patterns could be used to evaluate tinnitus evolution as well. The aim of the present study is to propose a methodology based on AERPs to evaluate the effectiveness of four acoustic therapies for tinnitus treatment.MethodsThe acoustic therapies were: (1) Tinnitus Retraining Therapy (TRT), (2) Auditory Discrimination Therapy (ADT), (3) Therapy for Enriched Acoustic Environment (TEAE), and (4) Binaural Beats Therapy (BBT). In addition, relaxing music was included as a placebo for both: tinnitus sufferers and healthy individuals. To meet this aim, 103 participants were recruited, 53% were females and 47% were males. All the participants were treated for 8 weeks with one of these five sounds, which were moreover tuned in accordance with the acoustic features of their tinnitus (if applied) and hearing loss. They were electroencephalographically monitored before and after their acoustic therapy, and wherefrom AERPs were estimated. The sound effect of acoustic therapies was evaluated by examining the area under the curve of those AERPs. Two parameters were obtained: (1) amplitude and (2) topographical distribution.ResultsThe findings of the investigation showed that after an 8-week treatment, TRT and ADT, respectively achieved significant neurophysiological changes over somatosensory and occipital regions. On one hand, TRT increased the tinnitus perception. On the other hand, ADT redirected the tinnitus attention, what in turn diminished the tinnitus perception. Tinnitus handicapped inventory outcomes verified these neurophysiological findings, revealing that 31% of patients in each group reported that TRT increased tinnitus perception, but ADT diminished it.DiscussionTinnitus has been identified as a multifactorial condition highly associated with hearing loss, age, sex, marital status, education, and even, employment. However, no conclusive evidence has been found yet. In this study, a significant (but low) correlation was found between tinnitus intensity and right ear hearing loss, left ear hearing loss, heart rate, area under the curve of AERPs, and acoustic therapy. This study raises the possibility to assign acoustic therapies by neurophysiological response of patient.https://www.frontiersin.org/articles/10.3389/fnins.2023.1059096/fulltinnitusacoustic therapyauditory event related potential (AERPs)area under a curve (AUC)audition (test)hospital anxiety and depression scale (HADS) |
| spellingShingle | Luz M. Alonso-Valerdi David I. Ibarra-Zárate Alma S. Torres-Torres Daniela M. Zolezzi Norberto E. Naal-Ruiz Janet Argüello-García Comparative analysis of acoustic therapies for tinnitus treatment based on auditory event-related potentials Frontiers in Neuroscience tinnitus acoustic therapy auditory event related potential (AERPs) area under a curve (AUC) audition (test) hospital anxiety and depression scale (HADS) |
| title | Comparative analysis of acoustic therapies for tinnitus treatment based on auditory event-related potentials |
| title_full | Comparative analysis of acoustic therapies for tinnitus treatment based on auditory event-related potentials |
| title_fullStr | Comparative analysis of acoustic therapies for tinnitus treatment based on auditory event-related potentials |
| title_full_unstemmed | Comparative analysis of acoustic therapies for tinnitus treatment based on auditory event-related potentials |
| title_short | Comparative analysis of acoustic therapies for tinnitus treatment based on auditory event-related potentials |
| title_sort | comparative analysis of acoustic therapies for tinnitus treatment based on auditory event related potentials |
| topic | tinnitus acoustic therapy auditory event related potential (AERPs) area under a curve (AUC) audition (test) hospital anxiety and depression scale (HADS) |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2023.1059096/full |
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