Multi-omic analyses reveal the unique properties of chia (Salvia hispanica) seed metabolism
Abstract Chia (Salvia hispanica) is an emerging crop considered a functional food containing important substances with multiple potential applications. However, the molecular basis of some relevant chia traits, such as seed mucilage and polyphenol content, remains to be discovered. This study genera...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-08-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-05192-4 |
| _version_ | 1797557211297218560 |
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| author | Gerardo Alejo-Jacuinde Héctor-Rogelio Nájera-González Ricardo A. Chávez Montes Cristian D. Gutierrez Reyes Alfonso Carlos Barragán-Rosillo Benjamin Perez Sanchez Yehia Mechref Damar López-Arredondo Lenin Yong-Villalobos Luis Herrera-Estrella |
| author_facet | Gerardo Alejo-Jacuinde Héctor-Rogelio Nájera-González Ricardo A. Chávez Montes Cristian D. Gutierrez Reyes Alfonso Carlos Barragán-Rosillo Benjamin Perez Sanchez Yehia Mechref Damar López-Arredondo Lenin Yong-Villalobos Luis Herrera-Estrella |
| author_sort | Gerardo Alejo-Jacuinde |
| collection | DOAJ |
| description | Abstract Chia (Salvia hispanica) is an emerging crop considered a functional food containing important substances with multiple potential applications. However, the molecular basis of some relevant chia traits, such as seed mucilage and polyphenol content, remains to be discovered. This study generates an improved chromosome-level reference of the chia genome, resolving some highly repetitive regions, describing methylation patterns, and refining genome annotation. Transcriptomic analysis shows that seeds exhibit a unique expression pattern compared to other organs and tissues. Thus, a metabolic and proteomic approach is implemented to study seed composition and seed-produced mucilage. The chia genome exhibits a significant expansion in mucilage synthesis genes (compared to Arabidopsis), and gene network analysis reveals potential regulators controlling seed mucilage production. Rosmarinic acid, a compound with enormous therapeutic potential, was classified as the most abundant polyphenol in seeds, and candidate genes for its complex pathway are described. Overall, this study provides important insights into the molecular basis for the unique characteristics of chia seeds. |
| first_indexed | 2024-03-10T17:14:09Z |
| format | Article |
| id | doaj.art-69a7063c51864248bf280819f1a81130 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-03-10T17:14:09Z |
| publishDate | 2023-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-69a7063c51864248bf280819f1a811302023-11-20T10:34:06ZengNature PortfolioCommunications Biology2399-36422023-08-016111310.1038/s42003-023-05192-4Multi-omic analyses reveal the unique properties of chia (Salvia hispanica) seed metabolismGerardo Alejo-Jacuinde0Héctor-Rogelio Nájera-González1Ricardo A. Chávez Montes2Cristian D. Gutierrez Reyes3Alfonso Carlos Barragán-Rosillo4Benjamin Perez Sanchez5Yehia Mechref6Damar López-Arredondo7Lenin Yong-Villalobos8Luis Herrera-Estrella9Department of Plant and Soil Science, Institute of Genomics for Crop Abiotic Stress Tolerance (IGCAST), Texas Tech UniversityDepartment of Plant and Soil Science, Institute of Genomics for Crop Abiotic Stress Tolerance (IGCAST), Texas Tech UniversityDepartment of Plant and Soil Science, Institute of Genomics for Crop Abiotic Stress Tolerance (IGCAST), Texas Tech UniversityDepartment of Chemistry and Biochemistry, Texas Tech UniversityDepartment of Plant and Soil Science, Institute of Genomics for Crop Abiotic Stress Tolerance (IGCAST), Texas Tech UniversityDepartment of Plant and Soil Science, Institute of Genomics for Crop Abiotic Stress Tolerance (IGCAST), Texas Tech UniversityDepartment of Chemistry and Biochemistry, Texas Tech UniversityDepartment of Plant and Soil Science, Institute of Genomics for Crop Abiotic Stress Tolerance (IGCAST), Texas Tech UniversityDepartment of Plant and Soil Science, Institute of Genomics for Crop Abiotic Stress Tolerance (IGCAST), Texas Tech UniversityDepartment of Plant and Soil Science, Institute of Genomics for Crop Abiotic Stress Tolerance (IGCAST), Texas Tech UniversityAbstract Chia (Salvia hispanica) is an emerging crop considered a functional food containing important substances with multiple potential applications. However, the molecular basis of some relevant chia traits, such as seed mucilage and polyphenol content, remains to be discovered. This study generates an improved chromosome-level reference of the chia genome, resolving some highly repetitive regions, describing methylation patterns, and refining genome annotation. Transcriptomic analysis shows that seeds exhibit a unique expression pattern compared to other organs and tissues. Thus, a metabolic and proteomic approach is implemented to study seed composition and seed-produced mucilage. The chia genome exhibits a significant expansion in mucilage synthesis genes (compared to Arabidopsis), and gene network analysis reveals potential regulators controlling seed mucilage production. Rosmarinic acid, a compound with enormous therapeutic potential, was classified as the most abundant polyphenol in seeds, and candidate genes for its complex pathway are described. Overall, this study provides important insights into the molecular basis for the unique characteristics of chia seeds.https://doi.org/10.1038/s42003-023-05192-4 |
| spellingShingle | Gerardo Alejo-Jacuinde Héctor-Rogelio Nájera-González Ricardo A. Chávez Montes Cristian D. Gutierrez Reyes Alfonso Carlos Barragán-Rosillo Benjamin Perez Sanchez Yehia Mechref Damar López-Arredondo Lenin Yong-Villalobos Luis Herrera-Estrella Multi-omic analyses reveal the unique properties of chia (Salvia hispanica) seed metabolism Communications Biology |
| title | Multi-omic analyses reveal the unique properties of chia (Salvia hispanica) seed metabolism |
| title_full | Multi-omic analyses reveal the unique properties of chia (Salvia hispanica) seed metabolism |
| title_fullStr | Multi-omic analyses reveal the unique properties of chia (Salvia hispanica) seed metabolism |
| title_full_unstemmed | Multi-omic analyses reveal the unique properties of chia (Salvia hispanica) seed metabolism |
| title_short | Multi-omic analyses reveal the unique properties of chia (Salvia hispanica) seed metabolism |
| title_sort | multi omic analyses reveal the unique properties of chia salvia hispanica seed metabolism |
| url | https://doi.org/10.1038/s42003-023-05192-4 |
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