Sex differences in the progression of glucose metabolism dysfunction in Alzheimer’s disease

Sex differences in the progression of glucose metabolism dysfunction in Alzheimer’s disease

Abstract Alzheimer’s disease (AD) is a common neurodegenerative disease characterized by amyloid plaques and impaired brain metabolism. Because women have a higher prevalence of AD than men, sex differences are of great interest. Using cross-sectional and longitudinal data, we showed sex-dependent m...

Full description

Bibliographic Details
Main Authors:	Jong-Chan Park, Hanbyeol Lim, Min Soo Byun, Dahyun Yi, Gihwan Byeon, Gijung Jung, Yu Kyeong Kim, Dong Young Lee, Sun-Ho Han, Inhee Mook-Jung
Format:	Article
Language:	English
Published:	Nature Publishing Group 2023-05-01
Series:	Experimental and Molecular Medicine
Online Access:	https://doi.org/10.1038/s12276-023-00993-3

Similar Items

Performance of the QPLEX™ Alz plus assay, a novel multiplex kit for screening cerebral amyloid deposition
by: Jong-Chan Park, et al.
Published: (2021-01-01)

Genetic associations of in vivo pathology influence Alzheimer’s disease susceptibility
by: Jieun Seo, et al.
Published: (2020-11-01)

Association of low meal frequency with decreased in vivo Alzheimer’s pathology
by: Jee Wook Kim, et al.
Published: (2022-11-01)

Amyloid beta-mediated epigenetic alteration of insulin-like growth factor binding protein 3 controls cell survival in Alzheimer's disease.
by: Hye Youn Sung, et al.
Published: (2014-01-01)

Low Serum Phosphorus Correlates with Cerebral Aβ Deposition in Cognitively Impaired Subjects: Results from the KBASE Study
by: Jong-Chan Park, et al.
Published: (2017-11-01)

Toward brain organoid-based precision medicine in neurodegenerative diseases
by: Jong-Chan Park, et al.
Published: (2022-10-01)

Synergistic interaction between APOE and family history of Alzheimer’s disease on cerebral amyloid deposition and glucose metabolism
by: Dahyun Yi, et al.
Published: (2018-08-01)

A logical network-based drug-screening platform for Alzheimer’s disease representing pathological features of human brain organoids
by: Jong-Chan Park, et al.
Published: (2021-01-01)

Body mass index and two-year change of in vivo Alzheimer’s disease pathologies in cognitively normal older adults
by: Seunghoon Lee, et al.
Published: (2023-06-01)

Gut microbiome alterations in preclinical Alzheimer’s disease
by: Joon Hyung Jung, et al.
Published: (2022-01-01)

The QPLEX™ Plus Assay Kit for the Early Clinical Diagnosis of Alzheimer’s Disease
by: Hunjong Na, et al.
Published: (2023-07-01)

Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death.
by: Moon-Yong Cha, et al.
Published: (2012-01-01)

Gut microbiome alterations in preclinical Alzheimer's disease.
by: Joon Hyung Jung, et al.
Published: (2022-01-01)

Blood Hemoglobin, in-vivo Alzheimer Pathologies, and Cognitive Impairment: A Cross-Sectional Study
by: Jee Wook Kim, et al.
Published: (2021-02-01)

Close Correlation of Monoamine Oxidase Activity with Progress of Alzheimer’s Disease in Mice, Observed by in Vivo Two-Photon Imaging
by: Dokyoung Kim, et al.
Published: (2016-12-01)

Mimicry of Central-Peripheral Immunity in Alzheimer's Disease and Discovery of Neurodegenerative Roles in Neutrophil
by: Joseph Park, et al.
Published: (2019-09-01)

Contributions of Microglia to Structural Synaptic Plasticity
by: Kyung Ho Kim, et al.
Published: (2013-01-01)

Serum Uric Acid, Alzheimer-Related Brain Changes, and Cognitive Impairment
by: Jee Wook Kim, et al.
Published: (2020-06-01)

Induction of neuronal death by microglial AGE-albumin: implications for Alzheimer's disease.
by: Kyunghee Byun, et al.
Published: (2012-01-01)

Synergistic interaction of high blood pressure and cerebral beta-amyloid on tau pathology
by: Taewon Kim, et al.
Published: (2022-12-01)

Associations of thyroid hormone serum levels with in-vivo Alzheimer’s disease pathologies
by: Hyo Jung Choi, et al.
Published: (2017-08-01)

Serum zinc levels and in vivo beta-amyloid deposition in the human brain
by: Jee Wook Kim, et al.
Published: (2021-11-01)

Molecular and functional signatures in a novel Alzheimer’s disease mouse model assessed by quantitative proteomics
by: Dong Kyu Kim, et al.
Published: (2018-01-01)

Brain somatic mutations observed in Alzheimer’s disease associated with aging and dysregulation of tau phosphorylation
by: Jun Sung Park, et al.
Published: (2019-07-01)

Dysfunctional Glucose Metabolism in Alzheimer’s Disease Onset and Potential Pharmacological Interventions
by: Vijay Kumar, et al.
Published: (2022-08-01)

Dysfunctional gene splicing in glucose metabolism may contribute to Alzheimer's disease
by: Shengfeng Deng, et al.
Published: (2023-03-01)

Association between brain amyloid deposition and longitudinal changes of white matter hyperintensities
by: Woo-Jin Cha, et al.
Published: (2024-03-01)

Global changes of phospholipids identified by MALDI imaging mass spectrometry in a mouse model of Alzheimer's disease
by: Ji Hye Hong, et al.
Published: (2016-01-01)

Region-specific association between basal blood insulin and cerebral glucose metabolism in older adults
by: Min Soo Byun, et al.
Published: (2019-01-01)

Deep learning application for the classification of Alzheimer’s disease using 18F-flortaucipir (AV-1451) tau positron emission tomography
by: Sang Won Park, et al.
Published: (2023-05-01)

Sex differences in the structural rich-club connectivity in patients with Alzheimer’s disease
by: Soo-Jong Kim, et al.
Published: (2023-09-01)

Machine learning application for classification of Alzheimer's disease stages using 18F-flortaucipir positron emission tomography
by: Sang Won Park, et al.
Published: (2023-04-01)

Effects of Chronic Tinnitus on Metabolic and Structural Changes in Subjects With Mild Cognitive Impairment
by: Sang-Yeon Lee, et al.
Published: (2020-11-01)

Environmentally Friendly Approach for the Production of Glucose and High-Purity Xylooligosaccharides from Edible Biomass Byproducts
by: Soo-Kyeong Jang, et al.
Published: (2020-11-01)

Early-Life Cognitive Activity Is Related to Reduced Neurodegeneration in Alzheimer Signature Regions in Late Life
by: Kang Ko, et al.
Published: (2018-03-01)

Sleep experiences during different lifetime periods and in vivo Alzheimer pathologies
by: Young Min Choe, et al.
Published: (2019-09-01)

Progress on the visual dysfunction after Alzheimer's disease and its mechanism
by: Qing Sang, et al.
Published: (2018-06-01)

Sex Differences in Large Artery Stiffness: Implications for Cerebrovascular Dysfunction and Alzheimer’s Disease
by: Mackenzie N. Kehmeier, et al.
Published: (2021-12-01)

lncRNAs UC.145 and PRKG1-AS1 Determine the Functional Output of DKK1 in Regulating the Wnt Signaling Pathway in Gastric Cancer
by: Jung-ho Yoon, et al.
Published: (2022-05-01)

A Case of Adrenoleukodystrophy Presenting as Progressive Cerebellar Dysfunction
by: Seunguk Jung, et al.
Published: (2009-10-01)