Current Concept and Epidemiology of Systemic Vasculitides

Although a new classification algorithm for systemic vasculitides was proposed by Watts et al. and the Chapel Hill Consensus Conference (CHCC) was updated in 2012, there are currently no validated diagnostic criteria for systemic vasculitides. The Diagnostic and Classification Criteria for Vasculiti...

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Main Authors: Takayuki Katsuyama, Ken-Ei Sada, Hirofumi Makino
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Allergology International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015300630
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author Takayuki Katsuyama
Ken-Ei Sada
Hirofumi Makino
author_facet Takayuki Katsuyama
Ken-Ei Sada
Hirofumi Makino
author_sort Takayuki Katsuyama
collection DOAJ
description Although a new classification algorithm for systemic vasculitides was proposed by Watts et al. and the Chapel Hill Consensus Conference (CHCC) was updated in 2012, there are currently no validated diagnostic criteria for systemic vasculitides. The Diagnostic and Classification Criteria for Vasculitis study (DCVAS) is a global study to develop and improve the diagnostic criteria for systemic vasculitides. The epidemiology of systemic vasculitides differs widely among countries. For example, in the case of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, patients with microscopic polyangiitis (MPA) and with positivity for MPO-ANCA are predominant in Asian countries, whereas patients with granulomatosis with polyangiitis (GPA) and with positivity for PR3-ANCA are predominant in northern Europe and the United States. Interstitial lung disease (ILD) occurs more frequently in Asian patients compared with patients in Europe. The incidence and the prevalence of large-vessel vasculitis also differ significantly. Giant cell arteritis (GCA) occurs frequently in northern Europe, unlike Takayasu arteritis (TAK). The ethnic and regional differences in the incidence, prevalence and clinical characteristics of patients with vasculitis should be recognized when we diagnose and treat patients with vasculitis using criteria, and should also be considered when interpreting the results from clinical studies.
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spelling doaj.art-69ac05b09bc047538c50eee32f6dd8292022-12-21T18:54:13ZengElsevierAllergology International1323-89302014-01-0163450551310.2332/allergolint.14-RAI-0778Current Concept and Epidemiology of Systemic VasculitidesTakayuki Katsuyama0Ken-Ei Sada1Hirofumi Makino2Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.Although a new classification algorithm for systemic vasculitides was proposed by Watts et al. and the Chapel Hill Consensus Conference (CHCC) was updated in 2012, there are currently no validated diagnostic criteria for systemic vasculitides. The Diagnostic and Classification Criteria for Vasculitis study (DCVAS) is a global study to develop and improve the diagnostic criteria for systemic vasculitides. The epidemiology of systemic vasculitides differs widely among countries. For example, in the case of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, patients with microscopic polyangiitis (MPA) and with positivity for MPO-ANCA are predominant in Asian countries, whereas patients with granulomatosis with polyangiitis (GPA) and with positivity for PR3-ANCA are predominant in northern Europe and the United States. Interstitial lung disease (ILD) occurs more frequently in Asian patients compared with patients in Europe. The incidence and the prevalence of large-vessel vasculitis also differ significantly. Giant cell arteritis (GCA) occurs frequently in northern Europe, unlike Takayasu arteritis (TAK). The ethnic and regional differences in the incidence, prevalence and clinical characteristics of patients with vasculitis should be recognized when we diagnose and treat patients with vasculitis using criteria, and should also be considered when interpreting the results from clinical studies.http://www.sciencedirect.com/science/article/pii/S1323893015300630antineutrophil cytoplasmic antibody-associated vasculitisChapel Hill Consensus Conference nomenclature of systemic vasculitidesepidemiologylarge vessel vasculitispolyarteritis nodosa
spellingShingle Takayuki Katsuyama
Ken-Ei Sada
Hirofumi Makino
Current Concept and Epidemiology of Systemic Vasculitides
Allergology International
antineutrophil cytoplasmic antibody-associated vasculitis
Chapel Hill Consensus Conference nomenclature of systemic vasculitides
epidemiology
large vessel vasculitis
polyarteritis nodosa
title Current Concept and Epidemiology of Systemic Vasculitides
title_full Current Concept and Epidemiology of Systemic Vasculitides
title_fullStr Current Concept and Epidemiology of Systemic Vasculitides
title_full_unstemmed Current Concept and Epidemiology of Systemic Vasculitides
title_short Current Concept and Epidemiology of Systemic Vasculitides
title_sort current concept and epidemiology of systemic vasculitides
topic antineutrophil cytoplasmic antibody-associated vasculitis
Chapel Hill Consensus Conference nomenclature of systemic vasculitides
epidemiology
large vessel vasculitis
polyarteritis nodosa
url http://www.sciencedirect.com/science/article/pii/S1323893015300630
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