The use of autogenous tooth bone graft is an efficient method of alveolar ridge preservation – meta-analysis and systematic review
Abstract Background Ridge resorption following tooth extraction may be reduced by alveolar ridge preservation (ARP). Previous randomized clinical trials and systematic reviews have suggested that autogenous tooth bone graft (ATB) can be an effective alternative material for ARP. However, the results...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-04-01
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| Series: | BMC Oral Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12903-023-02930-2 |
| _version_ | 1827961034274504704 |
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| author | Eleonora Solyom Eszter Szalai Márk László Czumbel Bence Szabo Szilárd Váncsa Krisztina Mikulas Zsombor Radoczy-Drajko Gabor Varga Péter Hegyi Balint Molnar Reka Fazekas |
| author_facet | Eleonora Solyom Eszter Szalai Márk László Czumbel Bence Szabo Szilárd Váncsa Krisztina Mikulas Zsombor Radoczy-Drajko Gabor Varga Péter Hegyi Balint Molnar Reka Fazekas |
| author_sort | Eleonora Solyom |
| collection | DOAJ |
| description | Abstract Background Ridge resorption following tooth extraction may be reduced by alveolar ridge preservation (ARP). Previous randomized clinical trials and systematic reviews have suggested that autogenous tooth bone graft (ATB) can be an effective alternative material for ARP. However, the results are heterogeneous. Therefore, our research aimed to evaluate the efficacy of ATB in ARP. Methods A systematic search was conducted in Cochrane Library, Embase, MEDLINE and Scopus for studies published from inception to 31 November 2021. We searched searched for randomized, non-randomized controlled trials and case series reporting on ATB use for ARP. The primary outcome was the ridge width difference pre- and post-surgery, measured in millimetres (mm) measured on CBCT (cone beam computed tomography). The secondary outcomes were the histological results. We followed the PRISMA2020 recommendations for reporting our systematic review and meta-analysis. Results The analysis included eight studies for the primary and six for the secondary outcomes. The meta-analysis revealed a positive ridge preservation effect with a pooled mean difference ridge width change of -0.72 mm. The pooled mean residual graft proportion was 11.61%, and the newly formed bone proportion was 40.23%. The pooled mean of newly formed bone proportion was higher in the group where ATB originated from both the root and crown of the tooth. Conclusions ATB is an effective particulate graft material in ARP. Complete demineralization of the ATB tends to decrease the proportion of newly formed bone. ATB can be an attractive option for ARP. Trial registration The study protocol was registered on PROSPERO (CRD42021287890). |
| first_indexed | 2024-04-09T16:20:25Z |
| format | Article |
| id | doaj.art-69aeaf0d2ff44ae590948e211cb4ae4a |
| institution | Directory Open Access Journal |
| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-04-09T16:20:25Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-69aeaf0d2ff44ae590948e211cb4ae4a2023-04-23T11:30:14ZengBMCBMC Oral Health1472-68312023-04-0123111110.1186/s12903-023-02930-2The use of autogenous tooth bone graft is an efficient method of alveolar ridge preservation – meta-analysis and systematic reviewEleonora Solyom0Eszter Szalai1Márk László Czumbel2Bence Szabo3Szilárd Váncsa4Krisztina Mikulas5Zsombor Radoczy-Drajko6Gabor Varga7Péter Hegyi8Balint Molnar9Reka Fazekas10Department of Periodontology, Semmelweis UniversityCentre for Translational Medicine, Semmelweis UniversityDepartment of Periodontology, Semmelweis UniversityCentre for Translational Medicine, Semmelweis UniversityCentre for Translational Medicine, Semmelweis UniversityCentre for Translational Medicine, Semmelweis UniversityDepartment of Periodontology, Semmelweis UniversityCentre for Translational Medicine, Semmelweis UniversityCentre for Translational Medicine, Semmelweis UniversityDepartment of Periodontology, Semmelweis UniversityCentre for Translational Medicine, Semmelweis UniversityAbstract Background Ridge resorption following tooth extraction may be reduced by alveolar ridge preservation (ARP). Previous randomized clinical trials and systematic reviews have suggested that autogenous tooth bone graft (ATB) can be an effective alternative material for ARP. However, the results are heterogeneous. Therefore, our research aimed to evaluate the efficacy of ATB in ARP. Methods A systematic search was conducted in Cochrane Library, Embase, MEDLINE and Scopus for studies published from inception to 31 November 2021. We searched searched for randomized, non-randomized controlled trials and case series reporting on ATB use for ARP. The primary outcome was the ridge width difference pre- and post-surgery, measured in millimetres (mm) measured on CBCT (cone beam computed tomography). The secondary outcomes were the histological results. We followed the PRISMA2020 recommendations for reporting our systematic review and meta-analysis. Results The analysis included eight studies for the primary and six for the secondary outcomes. The meta-analysis revealed a positive ridge preservation effect with a pooled mean difference ridge width change of -0.72 mm. The pooled mean residual graft proportion was 11.61%, and the newly formed bone proportion was 40.23%. The pooled mean of newly formed bone proportion was higher in the group where ATB originated from both the root and crown of the tooth. Conclusions ATB is an effective particulate graft material in ARP. Complete demineralization of the ATB tends to decrease the proportion of newly formed bone. ATB can be an attractive option for ARP. Trial registration The study protocol was registered on PROSPERO (CRD42021287890).https://doi.org/10.1186/s12903-023-02930-2Alveolar bone graftingAlveolar preservationAlveolar bone lossAlveolar processTooth socketSocket preservation |
| spellingShingle | Eleonora Solyom Eszter Szalai Márk László Czumbel Bence Szabo Szilárd Váncsa Krisztina Mikulas Zsombor Radoczy-Drajko Gabor Varga Péter Hegyi Balint Molnar Reka Fazekas The use of autogenous tooth bone graft is an efficient method of alveolar ridge preservation – meta-analysis and systematic review BMC Oral Health Alveolar bone grafting Alveolar preservation Alveolar bone loss Alveolar process Tooth socket Socket preservation |
| title | The use of autogenous tooth bone graft is an efficient method of alveolar ridge preservation – meta-analysis and systematic review |
| title_full | The use of autogenous tooth bone graft is an efficient method of alveolar ridge preservation – meta-analysis and systematic review |
| title_fullStr | The use of autogenous tooth bone graft is an efficient method of alveolar ridge preservation – meta-analysis and systematic review |
| title_full_unstemmed | The use of autogenous tooth bone graft is an efficient method of alveolar ridge preservation – meta-analysis and systematic review |
| title_short | The use of autogenous tooth bone graft is an efficient method of alveolar ridge preservation – meta-analysis and systematic review |
| title_sort | use of autogenous tooth bone graft is an efficient method of alveolar ridge preservation meta analysis and systematic review |
| topic | Alveolar bone grafting Alveolar preservation Alveolar bone loss Alveolar process Tooth socket Socket preservation |
| url | https://doi.org/10.1186/s12903-023-02930-2 |
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