Non-Mammalian Prdx6 Enzymes (Proteins with 1-Cys Prdx Mechanism) Display PLA2 Activity Similar to the Human Orthologue

Non-Mammalian Prdx6 Enzymes (Proteins with 1-Cys Prdx Mechanism) Display PLA2 Activity Similar to the Human Orthologue

Mammalian peroxiredoxin class 6 (Prdx6) are bifunctional enzymes. Non-mammalian Prdx6 enzymes display Cys-based peroxidase activity, but to date their putative phospholipase A2 (PLA2 activities) has not been experimentally investigated. Initially, we observed that five non-mammalian Prdx6 enzymes (e...

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Bibliographic Details
Main Authors: Renata Bannitz-Fernandes, Rogério Aleixo-Silva, João Paulo Silva, Chandra Dodia, Jose Pablo Vazquez-Medina, Jian-Qin Tao, Aron Fisher, Luis Netto
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Antioxidants
Subjects:
Peroxiredoxin
Prdx6
PLA2 activity
1-Cys Prdx
Online Access:http://www.mdpi.com/2076-3921/8/3/52

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