EFFECT OF CANAGLIFLOZIN ALONE AND IN COMBINATION WITH METFORMIN ON HORMONAL DERANGEMENTS AND ESTROUS CYCLE IN A POLYCYSTIC OVARY SYNDROME RAT MODEL

EFFECT OF CANAGLIFLOZIN ALONE AND IN COMBINATION WITH METFORMIN ON HORMONAL DERANGEMENTS AND ESTROUS CYCLE IN A POLYCYSTIC OVARY SYNDROME RAT MODEL

OBJECTIVE: To evaluate the effect of canagliflozin and metformin on the estrous cycle and hormonal derangement of letrozole induced polycystic ovarian syndrome (PCOS) in Sprague Dawly rats. METHODS:  Thirty six female adult non-pregnant Sprague Dawly rats were divided into six groups and all, exc...

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Bibliographic Details
Main Authors: Akfish Zaheer, Rabab Miraj, Nada Azam, Amir Hassan, Sadia Chiragh
Format: Article
Language:English
Published: Khyber Medical University 2021-06-01
Series:Khyber Medical University Journal
Subjects:
estradiol
estrogen
estrous cycle
follicle stimulating hormone
letrozole
luteinizing hormone
testosterone
canagliflozin
metformin
Online Access:https://www.kmuj.kmu.edu.pk/article/view/20602

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