Single-cell RNA-sequencing of stria vascularis cells in the adult Slc26a4 -/- mouse

Single-cell RNA-sequencing of stria vascularis cells in the adult Slc26a4 -/- mouse

Abstract Background The primary pathological alterations of Pendred syndrome are endolymphatic pH acidification and luminal enlargement of the inner ear. However, the molecular contributions of specific cell types remain poorly characterized. Therefore, we aimed to identify pH regulators in pendrin-...

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Bibliographic Details
Main Authors: Jin-Young Koh, Corentin Affortit, Paul T. Ranum, Cody West, William D. Walls, Hidekane Yoshimura, Jian Q. Shao, Brian Mostaert, Richard J.H. Smith
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Medical Genomics
Subjects:
Single-cell RNA sequencing
Stria vascularis cell
Spindle cells
Hearing loss
Slc26a4
Pendred syndrome
Online Access:https://doi.org/10.1186/s12920-023-01549-0

Internet

https://doi.org/10.1186/s12920-023-01549-0

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