Effects of intranasal medicines on microcirculatory blood flow of nasal cavity

The article describes the new method of assessment of microcirculatory blood perfusion and introduction of this method into the study of intranasal drugs effects on mucosal blood flow in the nasal cavity. The research work presents some different groups of drugs — decongestants, physical solutions f...

Full description

Bibliographic Details
Main Authors: Svistunov A.A., Mareev О.V., Mareev G.О., Bukreev I.S.
Format: Article
Language:Russian
Published: Saratov State Medical University 2012-09-01
Series:Саратовский научно-медицинский журнал
Subjects:
Online Access:http://www.ssmj.ru/system/files/201203-791-794.pdf
_version_ 1819031979831590912
author Svistunov A.A.
Mareev О.V.
Mareev G.О.
Bukreev I.S.
author_facet Svistunov A.A.
Mareev О.V.
Mareev G.О.
Bukreev I.S.
author_sort Svistunov A.A.
collection DOAJ
description The article describes the new method of assessment of microcirculatory blood perfusion and introduction of this method into the study of intranasal drugs effects on mucosal blood flow in the nasal cavity. The research work presents some different groups of drugs — decongestants, physical solutions for irrigation therapy and local corticosteroids. It has been revealed that intranasal decongestants have a significant effect on the intranasal blood flow, but their intake affects the mucosal membrane of the nasal cavity. Other drugs have not shown such negative effects and have not caused tachyphylaxis. Therefore these medicines may be recommended for more common use in ENT-practice.
first_indexed 2024-12-21T06:54:39Z
format Article
id doaj.art-69bc5681d0c6485781f09c87e91aef81
institution Directory Open Access Journal
issn 1995-0039
2076-2518
language Russian
last_indexed 2024-12-21T06:54:39Z
publishDate 2012-09-01
publisher Saratov State Medical University
record_format Article
series Саратовский научно-медицинский журнал
spelling doaj.art-69bc5681d0c6485781f09c87e91aef812022-12-21T19:12:21ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал1995-00392076-25182012-09-0183791794Effects of intranasal medicines on microcirculatory blood flow of nasal cavitySvistunov A.A.Mareev О.V.Mareev G.О.Bukreev I.S.The article describes the new method of assessment of microcirculatory blood perfusion and introduction of this method into the study of intranasal drugs effects on mucosal blood flow in the nasal cavity. The research work presents some different groups of drugs — decongestants, physical solutions for irrigation therapy and local corticosteroids. It has been revealed that intranasal decongestants have a significant effect on the intranasal blood flow, but their intake affects the mucosal membrane of the nasal cavity. Other drugs have not shown such negative effects and have not caused tachyphylaxis. Therefore these medicines may be recommended for more common use in ENT-practice.http://www.ssmj.ru/system/files/201203-791-794.pdfintranasal medicineslaser Doppler floumetrynasal microcirculation
spellingShingle Svistunov A.A.
Mareev О.V.
Mareev G.О.
Bukreev I.S.
Effects of intranasal medicines on microcirculatory blood flow of nasal cavity
Саратовский научно-медицинский журнал
intranasal medicines
laser Doppler floumetry
nasal microcirculation
title Effects of intranasal medicines on microcirculatory blood flow of nasal cavity
title_full Effects of intranasal medicines on microcirculatory blood flow of nasal cavity
title_fullStr Effects of intranasal medicines on microcirculatory blood flow of nasal cavity
title_full_unstemmed Effects of intranasal medicines on microcirculatory blood flow of nasal cavity
title_short Effects of intranasal medicines on microcirculatory blood flow of nasal cavity
title_sort effects of intranasal medicines on microcirculatory blood flow of nasal cavity
topic intranasal medicines
laser Doppler floumetry
nasal microcirculation
url http://www.ssmj.ru/system/files/201203-791-794.pdf
work_keys_str_mv AT svistunovaa effectsofintranasalmedicinesonmicrocirculatorybloodflowofnasalcavity
AT mareevov effectsofintranasalmedicinesonmicrocirculatorybloodflowofnasalcavity
AT mareevgo effectsofintranasalmedicinesonmicrocirculatorybloodflowofnasalcavity
AT bukreevis effectsofintranasalmedicinesonmicrocirculatorybloodflowofnasalcavity