Applying Meta-Analytic-Predictive Priors with the R Bayesian Evidence Synthesis Tools

Applying Meta-Analytic-Predictive Priors with the R Bayesian Evidence Synthesis Tools

Use of historical data in clinical trial design and analysis has shown various advantages such as reduction of number of subjects and increase of study power. The metaanalytic-predictive (MAP) approach accounts with a hierarchical model for between-trial heterogeneity in order to derive an informati...

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Bibliographic Details
Main Authors: Sebastian Weber, Yue Li, John W. Seaman III, Tomoyuki Kakizume, Heinz Schmidli
Format: Article
Language:English
Published: Foundation for Open Access Statistics 2021-11-01
Series:Journal of Statistical Software
Subjects:
bayesian inference
clinical trial
extrapolation
historical control
operating characteristics
prior
probability of success
robust analysis
Online Access:https://www.jstatsoft.org/index.php/jss/article/view/3820

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