The miR-200 family: multiple effects on gliomas
Lilei Peng,1 Jie Fu,2 Yang Ming1 1Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, People’s Republic of China; 2Department of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, People’s Republic of...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2018-07-01
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| Series: | Cancer Management and Research |
| Subjects: | |
| Online Access: | https://www.dovepress.com/the-mir-200-family-multiple-effects-on-gliomas-peer-reviewed-article-CMAR |
| _version_ | 1811328208926146560 |
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| author | Peng L Fu J Ming Y |
| author_facet | Peng L Fu J Ming Y |
| author_sort | Peng L |
| collection | DOAJ |
| description | Lilei Peng,1 Jie Fu,2 Yang Ming1 1Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, People’s Republic of China; 2Department of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, People’s Republic of China Abstract: Gliomas are the most common type of primary brain tumors. MicroRNAs (miRNAs) are small noncoding RNAs that can epigenetically regulate target gene expression. The microRNA 200 family includes miR-200a, 200b, 200c, 141 and 429. Numerous studies have indicated that members of the miR-200 family play an important role in glioma development and metastasis. In this review, we summarize the data from various studies and highlight the effects of miR-200 on glioma metastasis, therapeutic response and prognosis. Keywords: glioma, miR-200 family, metastasis, chemoresistance, radioresistance |
| first_indexed | 2024-04-13T15:22:16Z |
| format | Article |
| id | doaj.art-69c07443dcde4e6ab8e70a0c2c4cff6c |
| institution | Directory Open Access Journal |
| issn | 1179-1322 |
| language | English |
| last_indexed | 2024-04-13T15:22:16Z |
| publishDate | 2018-07-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Cancer Management and Research |
| spelling | doaj.art-69c07443dcde4e6ab8e70a0c2c4cff6c2022-12-22T02:41:38ZengDove Medical PressCancer Management and Research1179-13222018-07-01Volume 101987199239310The miR-200 family: multiple effects on gliomasPeng LFu JMing YLilei Peng,1 Jie Fu,2 Yang Ming1 1Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, People’s Republic of China; 2Department of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, People’s Republic of China Abstract: Gliomas are the most common type of primary brain tumors. MicroRNAs (miRNAs) are small noncoding RNAs that can epigenetically regulate target gene expression. The microRNA 200 family includes miR-200a, 200b, 200c, 141 and 429. Numerous studies have indicated that members of the miR-200 family play an important role in glioma development and metastasis. In this review, we summarize the data from various studies and highlight the effects of miR-200 on glioma metastasis, therapeutic response and prognosis. Keywords: glioma, miR-200 family, metastasis, chemoresistance, radioresistancehttps://www.dovepress.com/the-mir-200-family-multiple-effects-on-gliomas-peer-reviewed-article-CMARgliomamiR-200 familymetastasischemoresistanceradioresistance |
| spellingShingle | Peng L Fu J Ming Y The miR-200 family: multiple effects on gliomas Cancer Management and Research glioma miR-200 family metastasis chemoresistance radioresistance |
| title | The miR-200 family: multiple effects on gliomas |
| title_full | The miR-200 family: multiple effects on gliomas |
| title_fullStr | The miR-200 family: multiple effects on gliomas |
| title_full_unstemmed | The miR-200 family: multiple effects on gliomas |
| title_short | The miR-200 family: multiple effects on gliomas |
| title_sort | mir 200 family multiple effects on gliomas |
| topic | glioma miR-200 family metastasis chemoresistance radioresistance |
| url | https://www.dovepress.com/the-mir-200-family-multiple-effects-on-gliomas-peer-reviewed-article-CMAR |
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