Identification of cross-talk pathways and ferroptosis-related genes in periodontitis and type 2 diabetes mellitus by bioinformatics analysis and experimental validation

Identification of cross-talk pathways and ferroptosis-related genes in periodontitis and type 2 diabetes mellitus by bioinformatics analysis and experimental validation

PurposeThere is a bidirectional relationship between periodontitis and type 2 diabetes mellitus (T2DM). The aim of this study was to further explore the pathogenesis of this comorbidity, screen out ferroptosis-related genes involved in the pathological process, and predict potential drug targets to...

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Bibliographic Details
Main Authors: Shengyuan Pan, Bo Hu, Jicheng Sun, Zun Yang, Wenliang Yu, Zangmin He, Xiang Gao, Jinlin Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
ferroptosis
drug prediction
periodontitis
type 2 diabetes mellitus
pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1015491/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1015491/full

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