Comparative assessment of topical steroids, topical tretenoin (0.05%) and dithranol paste in alopecia areata

<b>Background:</b> There have been various controversial reports regarding the efficacy of topical agents in topical therapy of alopecia areata. <b> Aim:</b> The study aims to find out the effective ones among the readily available ones for a dermatologist. <b> Materi...

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Main Authors: Das Sudip, Ghorami R, Chatterjee T, Banerjee Gautam
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2010-01-01
Series:Indian Journal of Dermatology
Subjects:
Online Access:http://www.e-ijd.org/article.asp?issn=0019-5154;year=2010;volume=55;issue=2;spage=148;epage=149;aulast=Das
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author Das Sudip
Ghorami R
Chatterjee T
Banerjee Gautam
author_facet Das Sudip
Ghorami R
Chatterjee T
Banerjee Gautam
author_sort Das Sudip
collection DOAJ
description <b>Background:</b> There have been various controversial reports regarding the efficacy of topical agents in topical therapy of alopecia areata. <b> Aim:</b> The study aims to find out the effective ones among the readily available ones for a dermatologist. <b> Materials and Methods:</b> Eighty patients were chosen from the skin OPD of Bankura Sammilani Medical College, Bankura, West Bengal, after evaluating the exclusion criterions. Treatments were continued for 3 month period and a follow up after further 3 months. After dividing them into four groups-group-I (topical steroids), group-II (topical tretinoin 0.05&#x0025;) group-III (dithranol paste 0.25&#x0025;), and group-IV (white soft petrolatum jelly)-patients were evaluated. <b> Results:</b> Seventy percent of group-I, 55&#x0025; of group-II, 35&#x0025; of group-III, and 20&#x0025; of the control group (white soft petrolatum jelly) responded favorably. Side effects in the form of dermatitis and hyperpigmentation were seen in group-III. However, no patient discontinued from the study. <b> Conclusion:</b> We conclude that both topical steroids and tretinoin were fairly effective in limited variant of alopecia areata.
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spelling doaj.art-69c8e9d7f61e41d48b412a4bf6fd16422022-12-21T23:29:10ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112010-01-01552148149Comparative assessment of topical steroids, topical tretenoin (0.05&#x0025;) and dithranol paste in alopecia areataDas SudipGhorami RChatterjee TBanerjee Gautam<b>Background:</b> There have been various controversial reports regarding the efficacy of topical agents in topical therapy of alopecia areata. <b> Aim:</b> The study aims to find out the effective ones among the readily available ones for a dermatologist. <b> Materials and Methods:</b> Eighty patients were chosen from the skin OPD of Bankura Sammilani Medical College, Bankura, West Bengal, after evaluating the exclusion criterions. Treatments were continued for 3 month period and a follow up after further 3 months. After dividing them into four groups-group-I (topical steroids), group-II (topical tretinoin 0.05&#x0025;) group-III (dithranol paste 0.25&#x0025;), and group-IV (white soft petrolatum jelly)-patients were evaluated. <b> Results:</b> Seventy percent of group-I, 55&#x0025; of group-II, 35&#x0025; of group-III, and 20&#x0025; of the control group (white soft petrolatum jelly) responded favorably. Side effects in the form of dermatitis and hyperpigmentation were seen in group-III. However, no patient discontinued from the study. <b> Conclusion:</b> We conclude that both topical steroids and tretinoin were fairly effective in limited variant of alopecia areata.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2010;volume=55;issue=2;spage=148;epage=149;aulast=DasAlopecia areataanthralintopical steroidstretenoin
spellingShingle Das Sudip
Ghorami R
Chatterjee T
Banerjee Gautam
Comparative assessment of topical steroids, topical tretenoin (0.05&#x0025;) and dithranol paste in alopecia areata
Indian Journal of Dermatology
Alopecia areata
anthralin
topical steroids
tretenoin
title Comparative assessment of topical steroids, topical tretenoin (0.05&#x0025;) and dithranol paste in alopecia areata
title_full Comparative assessment of topical steroids, topical tretenoin (0.05&#x0025;) and dithranol paste in alopecia areata
title_fullStr Comparative assessment of topical steroids, topical tretenoin (0.05&#x0025;) and dithranol paste in alopecia areata
title_full_unstemmed Comparative assessment of topical steroids, topical tretenoin (0.05&#x0025;) and dithranol paste in alopecia areata
title_short Comparative assessment of topical steroids, topical tretenoin (0.05&#x0025;) and dithranol paste in alopecia areata
title_sort comparative assessment of topical steroids topical tretenoin 0 05 x0025 and dithranol paste in alopecia areata
topic Alopecia areata
anthralin
topical steroids
tretenoin
url http://www.e-ijd.org/article.asp?issn=0019-5154;year=2010;volume=55;issue=2;spage=148;epage=149;aulast=Das
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AT chatterjeet comparativeassessmentoftopicalsteroidstopicaltretenoin005x0025anddithranolpasteinalopeciaareata
AT banerjeegautam comparativeassessmentoftopicalsteroidstopicaltretenoin005x0025anddithranolpasteinalopeciaareata