Pharmacological evaluation of methanolic extract of Cyperus scariosus
The present study is aimed to investigate the phytochemical screening and biological activities of methanolic extract of Cyperus scariosus roots. Dried plant was grounded and extracted with methanol to prepare methanol crud extract. In vitro biological tests were conducted using this methanolic extr...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Bangladesh Pharmacological Society
2016-03-01
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| Series: | Bangladesh Journal of Pharmacology |
| Subjects: | |
| Online Access: | https://www.banglajol.info/index.php/BJP/article/view/23611 |
| _version_ | 1818113886670290944 |
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| author | Wasi Ullah Khan Rahmat Ali Khan Mushtaq Ahmed Latif Ullah Khan Muhammad Waqas Khan |
| author_facet | Wasi Ullah Khan Rahmat Ali Khan Mushtaq Ahmed Latif Ullah Khan Muhammad Waqas Khan |
| author_sort | Wasi Ullah Khan |
| collection | DOAJ |
| description | The present study is aimed to investigate the phytochemical screening and biological activities of methanolic extract of Cyperus scariosus roots. Dried plant was grounded and extracted with methanol to prepare methanol crud extract. In vitro biological tests were conducted using this methanolic extracts according to the standard procedure. 100% death rate of brine shrimp was perceived at 3 mg/mL of plant extract after 72 hours. The extract showed action against Aspergillus flavius i.e. 90% followed by A. niger (91%) while the highest activity was shown against A. fumegatrus (94%). Important scavenging results were detected during scavenging of free radicals viz; 92.2% against DPPH, 82.2% to ABTS, 75.8% to hydrogen peroxide, 88.1% to ?-carotene, 86.1% to hydroxyl radical and 89.4% against phosphomolybdate at 3 mg/mL were obtained. The results obtained in this study point out that extract showed significant biological activities which might be due to the presence of bioactive constituents. |
| first_indexed | 2024-12-11T03:41:58Z |
| format | Article |
| id | doaj.art-69ca0251181b41629fcd3db6a4f4a2ed |
| institution | Directory Open Access Journal |
| issn | 1991-0088 |
| language | English |
| last_indexed | 2024-12-11T03:41:58Z |
| publishDate | 2016-03-01 |
| publisher | Bangladesh Pharmacological Society |
| record_format | Article |
| series | Bangladesh Journal of Pharmacology |
| spelling | doaj.art-69ca0251181b41629fcd3db6a4f4a2ed2022-12-22T01:22:07ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882016-03-0111210.3329/bjp.v11i2.23611Pharmacological evaluation of methanolic extract of Cyperus scariosusWasi Ullah Khan0Rahmat Ali Khan1Mushtaq Ahmed2Latif Ullah Khan3Muhammad Waqas Khan4Department of Biotechnology, University of Science and Technology Bannu 28100, KPKDepartment of Biotechnology, University of Science and Technology Bannu 28100, KPKDepartment of Biotechnology, University of Science and Technology Bannu 28100, KPKDepartment of Biotechnology, University of Science and Technology Bannu 28100, KPKDepartment of Biotechnology, University of Science and Technology Bannu 28100, KPKThe present study is aimed to investigate the phytochemical screening and biological activities of methanolic extract of Cyperus scariosus roots. Dried plant was grounded and extracted with methanol to prepare methanol crud extract. In vitro biological tests were conducted using this methanolic extracts according to the standard procedure. 100% death rate of brine shrimp was perceived at 3 mg/mL of plant extract after 72 hours. The extract showed action against Aspergillus flavius i.e. 90% followed by A. niger (91%) while the highest activity was shown against A. fumegatrus (94%). Important scavenging results were detected during scavenging of free radicals viz; 92.2% against DPPH, 82.2% to ABTS, 75.8% to hydrogen peroxide, 88.1% to ?-carotene, 86.1% to hydroxyl radical and 89.4% against phosphomolybdate at 3 mg/mL were obtained. The results obtained in this study point out that extract showed significant biological activities which might be due to the presence of bioactive constituents.https://www.banglajol.info/index.php/BJP/article/view/23611Anti-oxidantCyperus scariosus |
| spellingShingle | Wasi Ullah Khan Rahmat Ali Khan Mushtaq Ahmed Latif Ullah Khan Muhammad Waqas Khan Pharmacological evaluation of methanolic extract of Cyperus scariosus Bangladesh Journal of Pharmacology Anti-oxidant Cyperus scariosus |
| title | Pharmacological evaluation of methanolic extract of Cyperus scariosus |
| title_full | Pharmacological evaluation of methanolic extract of Cyperus scariosus |
| title_fullStr | Pharmacological evaluation of methanolic extract of Cyperus scariosus |
| title_full_unstemmed | Pharmacological evaluation of methanolic extract of Cyperus scariosus |
| title_short | Pharmacological evaluation of methanolic extract of Cyperus scariosus |
| title_sort | pharmacological evaluation of methanolic extract of cyperus scariosus |
| topic | Anti-oxidant Cyperus scariosus |
| url | https://www.banglajol.info/index.php/BJP/article/view/23611 |
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