Intestinal-type adenocarcinoma presenting as a female periurethral mass
Abstract Background The periurethral mass in the female is a rare clinical entity and most of the lesions are benign. We present an unusual case of a periurethral mass found to be intestinal-type adenocarcinoma which has not been previously reported in the literature. Case presentation A 58-year-old...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-08-01
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| Series: | BMC Urology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12894-022-01077-6 |
| _version_ | 1811315219754909696 |
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| author | Ting Zeng Qiang Liu Shuxia Zhu Ruihua Xu |
| author_facet | Ting Zeng Qiang Liu Shuxia Zhu Ruihua Xu |
| author_sort | Ting Zeng |
| collection | DOAJ |
| description | Abstract Background The periurethral mass in the female is a rare clinical entity and most of the lesions are benign. We present an unusual case of a periurethral mass found to be intestinal-type adenocarcinoma which has not been previously reported in the literature. Case presentation A 58-year-old woman was referred to our hospital with acute urinary retention. She complained of frequency, urgency and progressive obstructive urinary symptoms for the last 3 months. A pelvic magnetic resonance imaging scan showed a soft tissue mass of 5 × 4 cm surrounding the entire urethra. A needle biopsy was done and revealed adenocarcinoma with intestinal-type features. The tumor was removed by a simultaneous laparoscopic abdominal and transperineal approach. The pathological results showed a positive surgical margin and urethra and vagina wall invasion. The neoplastic cells were positive for CK20, CDX-2, CerbB-2, MSH2, MSH6, MLH1, PMS2 and P53. The patient received adjuvant systemic chemotherapy comprising S-1 and oxaliplatin. Follow-up with pelvic MRI 6 months after surgery showed no signs of local recurrence. Conclusions We have reported the first case of the primary periurethral adenocarcinoma of intestinal type. There are currently no standardized protocols for the diagnosis, clinical course, and treatment of this rare tumor. This case study can aid decision-making regarding the diagnosis and treatment of this tumor. |
| first_indexed | 2024-04-13T11:27:34Z |
| format | Article |
| id | doaj.art-69cf8b2b760948658b486b1f2bc826a5 |
| institution | Directory Open Access Journal |
| issn | 1471-2490 |
| language | English |
| last_indexed | 2024-04-13T11:27:34Z |
| publishDate | 2022-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Urology |
| spelling | doaj.art-69cf8b2b760948658b486b1f2bc826a52022-12-22T02:48:40ZengBMCBMC Urology1471-24902022-08-012211410.1186/s12894-022-01077-6Intestinal-type adenocarcinoma presenting as a female periurethral massTing Zeng0Qiang Liu1Shuxia Zhu2Ruihua Xu3West China Hospital, Sichuan UniversityChengdu Second People’s HospitalChengdu Second People’s HospitalWest China Hospital, Sichuan UniversityAbstract Background The periurethral mass in the female is a rare clinical entity and most of the lesions are benign. We present an unusual case of a periurethral mass found to be intestinal-type adenocarcinoma which has not been previously reported in the literature. Case presentation A 58-year-old woman was referred to our hospital with acute urinary retention. She complained of frequency, urgency and progressive obstructive urinary symptoms for the last 3 months. A pelvic magnetic resonance imaging scan showed a soft tissue mass of 5 × 4 cm surrounding the entire urethra. A needle biopsy was done and revealed adenocarcinoma with intestinal-type features. The tumor was removed by a simultaneous laparoscopic abdominal and transperineal approach. The pathological results showed a positive surgical margin and urethra and vagina wall invasion. The neoplastic cells were positive for CK20, CDX-2, CerbB-2, MSH2, MSH6, MLH1, PMS2 and P53. The patient received adjuvant systemic chemotherapy comprising S-1 and oxaliplatin. Follow-up with pelvic MRI 6 months after surgery showed no signs of local recurrence. Conclusions We have reported the first case of the primary periurethral adenocarcinoma of intestinal type. There are currently no standardized protocols for the diagnosis, clinical course, and treatment of this rare tumor. This case study can aid decision-making regarding the diagnosis and treatment of this tumor.https://doi.org/10.1186/s12894-022-01077-6Periurethral massIntestinal-type adenocarcinomaCase report |
| spellingShingle | Ting Zeng Qiang Liu Shuxia Zhu Ruihua Xu Intestinal-type adenocarcinoma presenting as a female periurethral mass BMC Urology Periurethral mass Intestinal-type adenocarcinoma Case report |
| title | Intestinal-type adenocarcinoma presenting as a female periurethral mass |
| title_full | Intestinal-type adenocarcinoma presenting as a female periurethral mass |
| title_fullStr | Intestinal-type adenocarcinoma presenting as a female periurethral mass |
| title_full_unstemmed | Intestinal-type adenocarcinoma presenting as a female periurethral mass |
| title_short | Intestinal-type adenocarcinoma presenting as a female periurethral mass |
| title_sort | intestinal type adenocarcinoma presenting as a female periurethral mass |
| topic | Periurethral mass Intestinal-type adenocarcinoma Case report |
| url | https://doi.org/10.1186/s12894-022-01077-6 |
| work_keys_str_mv | AT tingzeng intestinaltypeadenocarcinomapresentingasafemaleperiurethralmass AT qiangliu intestinaltypeadenocarcinomapresentingasafemaleperiurethralmass AT shuxiazhu intestinaltypeadenocarcinomapresentingasafemaleperiurethralmass AT ruihuaxu intestinaltypeadenocarcinomapresentingasafemaleperiurethralmass |