Clinical case of statin-induced myopathy in female patient with compensated hypothyroidism and unfavorable polymorphic variant of SLCO1B1*5 (c.521T>C)
Statin-associated muscle symptoms are one of the statin-induced side effects. The incidence of the condition is increased by the presence of associated risk factors, one of which is hypothyroidism. The paper reports clinical case of statin-associated muscle symptoms in patient with compensated hypot...
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| Format: | Article |
| Language: | English |
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LLC "MEDIAFORMAT"
2021-05-01
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| Series: | Клинический разбор в общей медицине |
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| Online Access: | http://klin-razbor.ru/en/archive/2021/vol-2-5-2021/clinical-case-of-statin-induced-myopathy-in-female-patient-with-compensated-hypothyroidism-and-unfav_6041/ |
| _version_ | 1818898522491060224 |
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| author | Liya A. Lugovaya Alexey A. Nekrasov Leonid G. Strongin Tatyana A. Nekrasova |
| author_facet | Liya A. Lugovaya Alexey A. Nekrasov Leonid G. Strongin Tatyana A. Nekrasova |
| author_sort | Liya A. Lugovaya |
| collection | DOAJ |
| description | Statin-associated muscle symptoms are one of the statin-induced side effects. The incidence of the condition is increased by the presence of associated risk factors, one of which is hypothyroidism. The paper reports clinical case of statin-associated muscle symptoms in patient with compensated hypothyroidism carrying a SLCO1B1 mutation. Optimal assessment and treatment algorithms are discussed. |
| first_indexed | 2024-12-19T19:33:25Z |
| format | Article |
| id | doaj.art-69d1808f7ac64a41ae3eb9e997c4c675 |
| institution | Directory Open Access Journal |
| issn | 2713-2552 |
| language | English |
| last_indexed | 2024-12-19T19:33:25Z |
| publishDate | 2021-05-01 |
| publisher | LLC "MEDIAFORMAT" |
| record_format | Article |
| series | Клинический разбор в общей медицине |
| spelling | doaj.art-69d1808f7ac64a41ae3eb9e997c4c6752022-12-21T20:08:31ZengLLC "MEDIAFORMAT"Клинический разбор в общей медицине2713-25522021-05-0125212410.47407/kr2021.2.5.00066Clinical case of statin-induced myopathy in female patient with compensated hypothyroidism and unfavorable polymorphic variant of SLCO1B1*5 (c.521T>C)Liya A. Lugovaya0Alexey A. Nekrasov1Leonid G. Strongin2Tatyana A. Nekrasova3Privolzhsky Research Medical University, Nizhny Novgorod, RussiaPrivolzhsky Research Medical University, Nizhny Novgorod, RussiaPrivolzhsky Research Medical University, Nizhny Novgorod, RussiaPrivolzhsky Research Medical University, Nizhny Novgorod, RussiaStatin-associated muscle symptoms are one of the statin-induced side effects. The incidence of the condition is increased by the presence of associated risk factors, one of which is hypothyroidism. The paper reports clinical case of statin-associated muscle symptoms in patient with compensated hypothyroidism carrying a SLCO1B1 mutation. Optimal assessment and treatment algorithms are discussed.http://klin-razbor.ru/en/archive/2021/vol-2-5-2021/clinical-case-of-statin-induced-myopathy-in-female-patient-with-compensated-hypothyroidism-and-unfav_6041/compensated hypothyroidismstatinsmyopathyslco1b1 |
| spellingShingle | Liya A. Lugovaya Alexey A. Nekrasov Leonid G. Strongin Tatyana A. Nekrasova Clinical case of statin-induced myopathy in female patient with compensated hypothyroidism and unfavorable polymorphic variant of SLCO1B1*5 (c.521T>C) Клинический разбор в общей медицине compensated hypothyroidism statins myopathy slco1b1 |
| title | Clinical case of statin-induced myopathy in female patient with compensated hypothyroidism and unfavorable polymorphic variant of SLCO1B1*5 (c.521T>C) |
| title_full | Clinical case of statin-induced myopathy in female patient with compensated hypothyroidism and unfavorable polymorphic variant of SLCO1B1*5 (c.521T>C) |
| title_fullStr | Clinical case of statin-induced myopathy in female patient with compensated hypothyroidism and unfavorable polymorphic variant of SLCO1B1*5 (c.521T>C) |
| title_full_unstemmed | Clinical case of statin-induced myopathy in female patient with compensated hypothyroidism and unfavorable polymorphic variant of SLCO1B1*5 (c.521T>C) |
| title_short | Clinical case of statin-induced myopathy in female patient with compensated hypothyroidism and unfavorable polymorphic variant of SLCO1B1*5 (c.521T>C) |
| title_sort | clinical case of statin induced myopathy in female patient with compensated hypothyroidism and unfavorable polymorphic variant of slco1b1 5 c 521t c |
| topic | compensated hypothyroidism statins myopathy slco1b1 |
| url | http://klin-razbor.ru/en/archive/2021/vol-2-5-2021/clinical-case-of-statin-induced-myopathy-in-female-patient-with-compensated-hypothyroidism-and-unfav_6041/ |
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