Repeatability and agreement of AOCT-1000 M, RTVue XR and IOL master 500 in measuring corneal thickness mapping and axial length applying principle of optical coherence tomography

Abstract Purpose To evaluate the repeatability and agreement of Fourier-domain optical coherence tomography (AOCT-1000 M and RTVue XR) and partial coherence interferometry biometer (IOL Master 500) in measuring corneal thickness mapping and axial length respectively. Methods Corneal thickness was me...

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Main Authors: Hailong Ni, Suzhong Xu, Li Tian, Jieli Mao, Jing Li, Na Lin, Peike Hu, Zhiyi Wu, Xiang Chen, Zhishu Bao, Jingwei Zheng, Peihua Yan, Ruzhi Deng
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Medical Imaging
Subjects:
Online Access:https://doi.org/10.1186/s12880-023-01147-7
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author Hailong Ni
Suzhong Xu
Li Tian
Jieli Mao
Jing Li
Na Lin
Peike Hu
Zhiyi Wu
Xiang Chen
Zhishu Bao
Jingwei Zheng
Peihua Yan
Ruzhi Deng
author_facet Hailong Ni
Suzhong Xu
Li Tian
Jieli Mao
Jing Li
Na Lin
Peike Hu
Zhiyi Wu
Xiang Chen
Zhishu Bao
Jingwei Zheng
Peihua Yan
Ruzhi Deng
author_sort Hailong Ni
collection DOAJ
description Abstract Purpose To evaluate the repeatability and agreement of Fourier-domain optical coherence tomography (AOCT-1000 M and RTVue XR) and partial coherence interferometry biometer (IOL Master 500) in measuring corneal thickness mapping and axial length respectively. Methods Corneal thickness was measured by AOCT-1000 M and RTVue XR. Axial lengths were measured by AOCT-1000 M and IOL Master 500. The repeatability and agreement of corneal thickness and axial length were calculated in two groups of devices. The intraclass correlation coefficient (ICC) was used to verify the repeatability of the device. The 95% confidence interval of the difference compared to the set cut-off value was used to verify the agreement between the two devices. Results A total of 60 subjects with 58 eyes were included. The central corneal thickness measured by AOCT-1000 M and RTVue XR were 504.46 ± 42.53 μm and 504.43 ± 42.89 μm respectively. The average difference between groups was 0.03 ± 4.58 μm, and the 95% confidence interval was (-1.17, 1.24), which was far less than the set threshold value of 15 μm (P < 0.001). Both RTVue XR and AOCT-1000 M had very good ICC values of central corneal thickness (0.998 and 0.994, respectively). The average axial lengths measured by AOCT-1000 M and IOL Master 500 were 24.28 ± 1.25 mm and 24.29 ± 1.26 mm respectively and the 95% confidence interval was (-0.02, 0.01), which was less than the set threshold value of 0.15 mm (P < 0.001). The ICC for both devices were 1.000. Conclusion Good repeatability and agreement were seen in measurements of central corneal thickness and axial length by AOCT-1000 M.
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spelling doaj.art-69d1e56ceede489b8bbe1b63b8ba2ad42023-11-26T14:35:16ZengBMCBMC Medical Imaging1471-23422023-11-0123111110.1186/s12880-023-01147-7Repeatability and agreement of AOCT-1000 M, RTVue XR and IOL master 500 in measuring corneal thickness mapping and axial length applying principle of optical coherence tomographyHailong Ni0Suzhong Xu1Li Tian2Jieli Mao3Jing Li4Na Lin5Peike Hu6Zhiyi Wu7Xiang Chen8Zhishu Bao9Jingwei Zheng10Peihua Yan11Ruzhi Deng12Eye Center, Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEye hospital of Wenzhou Medical UniversityEye hospital of Wenzhou Medical UniversityEye hospital of Wenzhou Medical UniversityEye hospital of Wenzhou Medical UniversityEye hospital of Wenzhou Medical UniversityEye Center, Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEye Center, Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEye Center, Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEye hospital of Wenzhou Medical UniversityEye hospital of Wenzhou Medical UniversityVision X Medical Technology Co., Ltd.Eye hospital of Wenzhou Medical UniversityAbstract Purpose To evaluate the repeatability and agreement of Fourier-domain optical coherence tomography (AOCT-1000 M and RTVue XR) and partial coherence interferometry biometer (IOL Master 500) in measuring corneal thickness mapping and axial length respectively. Methods Corneal thickness was measured by AOCT-1000 M and RTVue XR. Axial lengths were measured by AOCT-1000 M and IOL Master 500. The repeatability and agreement of corneal thickness and axial length were calculated in two groups of devices. The intraclass correlation coefficient (ICC) was used to verify the repeatability of the device. The 95% confidence interval of the difference compared to the set cut-off value was used to verify the agreement between the two devices. Results A total of 60 subjects with 58 eyes were included. The central corneal thickness measured by AOCT-1000 M and RTVue XR were 504.46 ± 42.53 μm and 504.43 ± 42.89 μm respectively. The average difference between groups was 0.03 ± 4.58 μm, and the 95% confidence interval was (-1.17, 1.24), which was far less than the set threshold value of 15 μm (P < 0.001). Both RTVue XR and AOCT-1000 M had very good ICC values of central corneal thickness (0.998 and 0.994, respectively). The average axial lengths measured by AOCT-1000 M and IOL Master 500 were 24.28 ± 1.25 mm and 24.29 ± 1.26 mm respectively and the 95% confidence interval was (-0.02, 0.01), which was less than the set threshold value of 0.15 mm (P < 0.001). The ICC for both devices were 1.000. Conclusion Good repeatability and agreement were seen in measurements of central corneal thickness and axial length by AOCT-1000 M.https://doi.org/10.1186/s12880-023-01147-7RepeatabilityAgreementCentral corneal thicknessAxial lengthRTVue XRAOCT-1000 M
spellingShingle Hailong Ni
Suzhong Xu
Li Tian
Jieli Mao
Jing Li
Na Lin
Peike Hu
Zhiyi Wu
Xiang Chen
Zhishu Bao
Jingwei Zheng
Peihua Yan
Ruzhi Deng
Repeatability and agreement of AOCT-1000 M, RTVue XR and IOL master 500 in measuring corneal thickness mapping and axial length applying principle of optical coherence tomography
BMC Medical Imaging
Repeatability
Agreement
Central corneal thickness
Axial length
RTVue XR
AOCT-1000 M
title Repeatability and agreement of AOCT-1000 M, RTVue XR and IOL master 500 in measuring corneal thickness mapping and axial length applying principle of optical coherence tomography
title_full Repeatability and agreement of AOCT-1000 M, RTVue XR and IOL master 500 in measuring corneal thickness mapping and axial length applying principle of optical coherence tomography
title_fullStr Repeatability and agreement of AOCT-1000 M, RTVue XR and IOL master 500 in measuring corneal thickness mapping and axial length applying principle of optical coherence tomography
title_full_unstemmed Repeatability and agreement of AOCT-1000 M, RTVue XR and IOL master 500 in measuring corneal thickness mapping and axial length applying principle of optical coherence tomography
title_short Repeatability and agreement of AOCT-1000 M, RTVue XR and IOL master 500 in measuring corneal thickness mapping and axial length applying principle of optical coherence tomography
title_sort repeatability and agreement of aoct 1000 m rtvue xr and iol master 500 in measuring corneal thickness mapping and axial length applying principle of optical coherence tomography
topic Repeatability
Agreement
Central corneal thickness
Axial length
RTVue XR
AOCT-1000 M
url https://doi.org/10.1186/s12880-023-01147-7
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