Nuclear PI3K signaling in cell growth and tumorigenesis
The PI3K/Akt signaling pathway is a major driving force in a variety of cellular functions. Dysregulation of this pathway has been implicated in many human diseases including cancer. While the activity of the cytoplasmic PI3K/Akt pathway has been extensively studied, the functions of these molecules...
Main Authors: | William J Davis, Peter Z Lehmann, Weimin eLi |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-04-01
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Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00024/full |
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