Features the interaction of functional and metabolic remodeling of myocardium in comorbid course of ischemic heart disease and 2 type diabetes mellitus

Features the interaction of functional and metabolic remodeling of myocardium in comorbid course of ischemic heart disease and 2 type diabetes mellitus

Background: Metabolic and structural changes in cardiomyocytes in diabetes mellitus lead to aggravation of contractile myocardial dysfunction in coronary heart disease (CHD). The contractility dysfunction of cardiomyocytes is determined by a change in the levels of sarcoplasmic reticulum (SR) Ca2+-A...

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Bibliographic Details
Main Authors:	Sergey A. Afanasiev, Dina S. Kondratieva, Margarita V. Egorova, Shamil D. Akhmedov, Olesya V. Budnikova, Sergey V. Popov
Format:	Article
Language:	English
Published:	Endocrinology Research Centre 2019-03-01
Series:	Сахарный диабет
Subjects:	coronary heart disease type 2 diabetes mellitus contractility of isolated trabeculae ca2+-atpase, succinate dehydrogenase lactate dehydrogenase oxidative phosphorylation
Online Access:	https://www.dia-endojournals.ru/jour/article/view/9735

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