Titanium-niobium pentoxide composites for biomedical applications
The strength of titanium scaffolds with the introduction of high porosity decreases dramatically and may become inadequate for load bearing in biomedical applications. To simultaneously meet the requirements of biocompatibility, low elastic modulus and appropriate strength for orthopedic implant mat...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2016-12-01
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| Series: | Bioactive Materials |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X16300287 |
| _version_ | 1797203640261279744 |
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| author | Yuncang Li Khurram S. Munir Jixing Lin Cuie Wen |
| author_facet | Yuncang Li Khurram S. Munir Jixing Lin Cuie Wen |
| author_sort | Yuncang Li |
| collection | DOAJ |
| description | The strength of titanium scaffolds with the introduction of high porosity decreases dramatically and may become inadequate for load bearing in biomedical applications. To simultaneously meet the requirements of biocompatibility, low elastic modulus and appropriate strength for orthopedic implant materials, it is highly desirable to develop new biocompatible titanium based materials with enhanced strength. In this study, we developed a niobium pentoxide (Nb2O5) reinforced titanium composite via powder metallurgy for biomedical applications. The strength of the Nb2O5 reinforced titanium composites (Ti-Nb2O5) is significantly higher than that of pure titanium. Cell culture results revealed that the Ti-Nb2O5 composite exhibits excellent biocompatibility and cell adhesion. Human osteoblast-like cells grew and spread healthily on the surface of the Ti-Nb2O5 composite. Our study demonstrated that Nb2O5 reinforced titanium composite is a promising implant material by virtue of its high mechanical strength and excellent biocompatibility. |
| first_indexed | 2024-04-24T08:22:33Z |
| format | Article |
| id | doaj.art-69dca02ac21044fd91624462fef18818 |
| institution | Directory Open Access Journal |
| issn | 2452-199X |
| language | English |
| last_indexed | 2024-04-24T08:22:33Z |
| publishDate | 2016-12-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Bioactive Materials |
| spelling | doaj.art-69dca02ac21044fd91624462fef188182024-04-17T00:34:28ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2016-12-011212713110.1016/j.bioactmat.2016.10.001Titanium-niobium pentoxide composites for biomedical applicationsYuncang Li0Khurram S. Munir1Jixing Lin2Cuie Wen3School of Engineering, RMIT University, Melbourne, Victoria 3001, AustraliaSchool of Engineering, RMIT University, Melbourne, Victoria 3001, AustraliaDepartment of Materials Science and Engineering, Jilin University, Changchun, Jilin 130025, ChinaSchool of Engineering, RMIT University, Melbourne, Victoria 3001, AustraliaThe strength of titanium scaffolds with the introduction of high porosity decreases dramatically and may become inadequate for load bearing in biomedical applications. To simultaneously meet the requirements of biocompatibility, low elastic modulus and appropriate strength for orthopedic implant materials, it is highly desirable to develop new biocompatible titanium based materials with enhanced strength. In this study, we developed a niobium pentoxide (Nb2O5) reinforced titanium composite via powder metallurgy for biomedical applications. The strength of the Nb2O5 reinforced titanium composites (Ti-Nb2O5) is significantly higher than that of pure titanium. Cell culture results revealed that the Ti-Nb2O5 composite exhibits excellent biocompatibility and cell adhesion. Human osteoblast-like cells grew and spread healthily on the surface of the Ti-Nb2O5 composite. Our study demonstrated that Nb2O5 reinforced titanium composite is a promising implant material by virtue of its high mechanical strength and excellent biocompatibility.http://www.sciencedirect.com/science/article/pii/S2452199X16300287Titanium-niobium pentoxide compositeParticulate-reinforcementOrthopedic implantMechanical propertyBiocompatibility |
| spellingShingle | Yuncang Li Khurram S. Munir Jixing Lin Cuie Wen Titanium-niobium pentoxide composites for biomedical applications Bioactive Materials Titanium-niobium pentoxide composite Particulate-reinforcement Orthopedic implant Mechanical property Biocompatibility |
| title | Titanium-niobium pentoxide composites for biomedical applications |
| title_full | Titanium-niobium pentoxide composites for biomedical applications |
| title_fullStr | Titanium-niobium pentoxide composites for biomedical applications |
| title_full_unstemmed | Titanium-niobium pentoxide composites for biomedical applications |
| title_short | Titanium-niobium pentoxide composites for biomedical applications |
| title_sort | titanium niobium pentoxide composites for biomedical applications |
| topic | Titanium-niobium pentoxide composite Particulate-reinforcement Orthopedic implant Mechanical property Biocompatibility |
| url | http://www.sciencedirect.com/science/article/pii/S2452199X16300287 |
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