U-Net-Based Models towards Optimal MR Brain Image Segmentation

Brain tumor segmentation from MRIs has always been a challenging task for radiologists, therefore, an automatic and generalized system to address this task is needed. Among all other deep learning techniques used in medical imaging, U-Net-based variants are the most used models found in the literatu...

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Main Authors: Rammah Yousef, Shakir Khan, Gaurav Gupta, Tamanna Siddiqui, Bader M. Albahlal, Saad Abdullah Alajlan, Mohd Anul Haq
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/13/9/1624
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author Rammah Yousef
Shakir Khan
Gaurav Gupta
Tamanna Siddiqui
Bader M. Albahlal
Saad Abdullah Alajlan
Mohd Anul Haq
author_facet Rammah Yousef
Shakir Khan
Gaurav Gupta
Tamanna Siddiqui
Bader M. Albahlal
Saad Abdullah Alajlan
Mohd Anul Haq
author_sort Rammah Yousef
collection DOAJ
description Brain tumor segmentation from MRIs has always been a challenging task for radiologists, therefore, an automatic and generalized system to address this task is needed. Among all other deep learning techniques used in medical imaging, U-Net-based variants are the most used models found in the literature to segment medical images with respect to different modalities. Therefore, the goal of this paper is to examine the numerous advancements and innovations in the U-Net architecture, as well as recent trends, with the aim of highlighting the ongoing potential of U-Net being used to better the performance of brain tumor segmentation. Furthermore, we provide a quantitative comparison of different U-Net architectures to highlight the performance and the evolution of this network from an optimization perspective. In addition to that, we have experimented with four U-Net architectures (3D U-Net, Attention U-Net, R2 Attention U-Net, and modified 3D U-Net) on the BraTS 2020 dataset for brain tumor segmentation to provide a better overview of this architecture’s performance in terms of Dice score and Hausdorff distance 95%. Finally, we analyze the limitations and challenges of medical image analysis to provide a critical discussion about the importance of developing new architectures in terms of optimization.
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spelling doaj.art-69dd237b7a1246b28a184700e73c66292023-11-17T22:46:13ZengMDPI AGDiagnostics2075-44182023-05-01139162410.3390/diagnostics13091624U-Net-Based Models towards Optimal MR Brain Image SegmentationRammah Yousef0Shakir Khan1Gaurav Gupta2Tamanna Siddiqui3Bader M. Albahlal4Saad Abdullah Alajlan5Mohd Anul Haq6Yogananda School of AI, Computers and Data Sciences, Shoolini University, Solan 173229, IndiaCollege of Computer and Information Sciences, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi ArabiaYogananda School of AI, Computers and Data Sciences, Shoolini University, Solan 173229, IndiaDepartment of Computer Science, Aligarh Muslim University, Aligarh 202001, IndiaCollege of Computer and Information Sciences, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi ArabiaCollege of Computer and Information Sciences, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi ArabiaDepartment of Computer Science, College of Computer and Information Sciences, Majmaah University, Al-Majmaah 11952, Saudi ArabiaBrain tumor segmentation from MRIs has always been a challenging task for radiologists, therefore, an automatic and generalized system to address this task is needed. Among all other deep learning techniques used in medical imaging, U-Net-based variants are the most used models found in the literature to segment medical images with respect to different modalities. Therefore, the goal of this paper is to examine the numerous advancements and innovations in the U-Net architecture, as well as recent trends, with the aim of highlighting the ongoing potential of U-Net being used to better the performance of brain tumor segmentation. Furthermore, we provide a quantitative comparison of different U-Net architectures to highlight the performance and the evolution of this network from an optimization perspective. In addition to that, we have experimented with four U-Net architectures (3D U-Net, Attention U-Net, R2 Attention U-Net, and modified 3D U-Net) on the BraTS 2020 dataset for brain tumor segmentation to provide a better overview of this architecture’s performance in terms of Dice score and Hausdorff distance 95%. Finally, we analyze the limitations and challenges of medical image analysis to provide a critical discussion about the importance of developing new architectures in terms of optimization.https://www.mdpi.com/2075-4418/13/9/1624U-NetMR brain imagesloss functionsimage segmentationoptimizationdeep learning
spellingShingle Rammah Yousef
Shakir Khan
Gaurav Gupta
Tamanna Siddiqui
Bader M. Albahlal
Saad Abdullah Alajlan
Mohd Anul Haq
U-Net-Based Models towards Optimal MR Brain Image Segmentation
Diagnostics
U-Net
MR brain images
loss functions
image segmentation
optimization
deep learning
title U-Net-Based Models towards Optimal MR Brain Image Segmentation
title_full U-Net-Based Models towards Optimal MR Brain Image Segmentation
title_fullStr U-Net-Based Models towards Optimal MR Brain Image Segmentation
title_full_unstemmed U-Net-Based Models towards Optimal MR Brain Image Segmentation
title_short U-Net-Based Models towards Optimal MR Brain Image Segmentation
title_sort u net based models towards optimal mr brain image segmentation
topic U-Net
MR brain images
loss functions
image segmentation
optimization
deep learning
url https://www.mdpi.com/2075-4418/13/9/1624
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AT badermalbahlal unetbasedmodelstowardsoptimalmrbrainimagesegmentation
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