Extensive age-dependent loss of antibody diversity in naturally short-lived turquoise killifish
Aging individuals exhibit a pervasive decline in adaptive immune function, with important implications for health and lifespan. Previous studies have found a pervasive loss of immune-repertoire diversity in human peripheral blood during aging; however, little is known about repertoire aging in other...
Main Authors: | William John Bradshaw, Michael Poeschla, Aleksandra Placzek, Samuel Kean, Dario Riccardo Valenzano |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/65117 |
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