Techniques and Technologies to Improve Vein Graft Patency in Coronary Surgery

Vein grafts are the most used conduits in coronary artery bypass grafting (CABG), even though many studies have suggested their lower patency compared to arterial alternatives. We have reviewed the techniques and technologies that have been investigated over the years with the aim of improving the q...

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Main Authors: Marco Gemelli, Mariangela Addonizio, Veronica Geatti, Michele Gallo, Lauren K. Dixon, Mark S. Slaughter, Gino Gerosa
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Medical Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3271/12/1/6
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author Marco Gemelli
Mariangela Addonizio
Veronica Geatti
Michele Gallo
Lauren K. Dixon
Mark S. Slaughter
Gino Gerosa
author_facet Marco Gemelli
Mariangela Addonizio
Veronica Geatti
Michele Gallo
Lauren K. Dixon
Mark S. Slaughter
Gino Gerosa
author_sort Marco Gemelli
collection DOAJ
description Vein grafts are the most used conduits in coronary artery bypass grafting (CABG), even though many studies have suggested their lower patency compared to arterial alternatives. We have reviewed the techniques and technologies that have been investigated over the years with the aim of improving the quality of these conduits. We found that preoperative and postoperative optimal medical therapy and no-touch harvesting techniques have the strongest evidence for optimizing vein graft patency. On the other hand, the use of venous external support, endoscopic harvesting, vein preservation solution and anastomosis, and graft configuration need further investigation. We have also analyzed strategies to treat vein graft failure: when feasible, re-doing the CABG and native vessel primary coronary intervention (PCI) are the best options, followed by percutaneous procedures targeting the failed grafts.
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spelling doaj.art-69eb4d0856124255b79f7bf8bc48c1c52024-03-27T13:53:57ZengMDPI AGMedical Sciences2076-32712024-01-01121610.3390/medsci12010006Techniques and Technologies to Improve Vein Graft Patency in Coronary SurgeryMarco Gemelli0Mariangela Addonizio1Veronica Geatti2Michele Gallo3Lauren K. Dixon4Mark S. Slaughter5Gino Gerosa6Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, 35128 Padova, ItalyCardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, 35128 Padova, ItalyCardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, 35128 Padova, ItalyDepartment of Cardiothoracic Surgery, University of Louisville, Louisville, KY 40292, USAClinical Effectiveness Unit, The Royal College of Surgeons of England, London WC2A 3PE, UKDepartment of Cardiothoracic Surgery, University of Louisville, Louisville, KY 40292, USACardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, 35128 Padova, ItalyVein grafts are the most used conduits in coronary artery bypass grafting (CABG), even though many studies have suggested their lower patency compared to arterial alternatives. We have reviewed the techniques and technologies that have been investigated over the years with the aim of improving the quality of these conduits. We found that preoperative and postoperative optimal medical therapy and no-touch harvesting techniques have the strongest evidence for optimizing vein graft patency. On the other hand, the use of venous external support, endoscopic harvesting, vein preservation solution and anastomosis, and graft configuration need further investigation. We have also analyzed strategies to treat vein graft failure: when feasible, re-doing the CABG and native vessel primary coronary intervention (PCI) are the best options, followed by percutaneous procedures targeting the failed grafts.https://www.mdpi.com/2076-3271/12/1/6CABGvein graftgraft patencylong-term outcomesvein graft failure
spellingShingle Marco Gemelli
Mariangela Addonizio
Veronica Geatti
Michele Gallo
Lauren K. Dixon
Mark S. Slaughter
Gino Gerosa
Techniques and Technologies to Improve Vein Graft Patency in Coronary Surgery
Medical Sciences
CABG
vein graft
graft patency
long-term outcomes
vein graft failure
title Techniques and Technologies to Improve Vein Graft Patency in Coronary Surgery
title_full Techniques and Technologies to Improve Vein Graft Patency in Coronary Surgery
title_fullStr Techniques and Technologies to Improve Vein Graft Patency in Coronary Surgery
title_full_unstemmed Techniques and Technologies to Improve Vein Graft Patency in Coronary Surgery
title_short Techniques and Technologies to Improve Vein Graft Patency in Coronary Surgery
title_sort techniques and technologies to improve vein graft patency in coronary surgery
topic CABG
vein graft
graft patency
long-term outcomes
vein graft failure
url https://www.mdpi.com/2076-3271/12/1/6
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AT michelegallo techniquesandtechnologiestoimproveveingraftpatencyincoronarysurgery
AT laurenkdixon techniquesandtechnologiestoimproveveingraftpatencyincoronarysurgery
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