MiR-103 alleviates autophagy and apoptosis by regulating SOX2 in LPS-injured PC12 cells and SCI rats

MiR-103 alleviates autophagy and apoptosis by regulating SOX2 in LPS-injured PC12 cells and SCI rats

Objective(s): Recent studies revealed that microRNAs (miRNAs) may play crucial roles in the responses and pathologic processes of spinal cord injury (SCI). This study aimed to investigate the effect and the molecular basis of miR-103 on LPS-induced injuries in PC12 cells in vitro and SCI rats in viv...

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Bibliographic Details
Main Authors: Guowei Li, Tao Chen, Yingxian Zhu, Xiaoyu Xiao, Juyuan Bu, Zongwen Huang
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-03-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Apoptosis
Autophagy
MAPK/ERK and JAK/STAT pathway
miR-103
SOX2
Spinal cord injury
Online Access:http://ijbms.mums.ac.ir/article_10146_9c79f4c08b460f77d0071df7a7fc1e3e.pdf

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