Underlying lung disease and exposure to terrestrial moderate and high altitude: personalised risk assessment

Abstract Once reserved for the fittest, worldwide altitude travel has become increasingly accessible for ageing and less fit people. As a result, more and more individuals with varying degrees of respiratory conditions wish to travel to altitude destinations. Exposure to a hypobaric hypoxic environm...

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Main Authors: Kirsten Holthof, Pierre-Olivier Bridevaux, Isabelle Frésard
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Pulmonary Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12890-022-01979-z
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author Kirsten Holthof
Pierre-Olivier Bridevaux
Isabelle Frésard
author_facet Kirsten Holthof
Pierre-Olivier Bridevaux
Isabelle Frésard
author_sort Kirsten Holthof
collection DOAJ
description Abstract Once reserved for the fittest, worldwide altitude travel has become increasingly accessible for ageing and less fit people. As a result, more and more individuals with varying degrees of respiratory conditions wish to travel to altitude destinations. Exposure to a hypobaric hypoxic environment at altitude challenges the human body and leads to a series of physiological adaptive mechanisms. These changes, as well as general altitude related risks have been well described in healthy individuals. However, limited data are available on the risks faced by patients with pre-existing lung disease. A comprehensive literature search was conducted. First, we aimed in this review to evaluate health risks of moderate and high terrestrial altitude travel by patients with pre-existing lung disease, including chronic obstructive pulmonary disease, sleep apnoea syndrome, asthma, bullous or cystic lung disease, pulmonary hypertension and interstitial lung disease. Second, we seek to summarise for each underlying lung disease, a personalized pre-travel assessment as well as measures to prevent, monitor and mitigate worsening of underlying respiratory disease during travel.
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spelling doaj.art-69ec5eba8be14f2d89a43b752bf3b0252022-12-22T00:39:58ZengBMCBMC Pulmonary Medicine1471-24662022-05-0122111210.1186/s12890-022-01979-zUnderlying lung disease and exposure to terrestrial moderate and high altitude: personalised risk assessmentKirsten Holthof0Pierre-Olivier Bridevaux1Isabelle Frésard2Service de pneumologie, Centre Hospitalier du Valais RomandService de pneumologie, Centre Hospitalier du Valais RomandService de pneumologie, Centre Hospitalier du Valais RomandAbstract Once reserved for the fittest, worldwide altitude travel has become increasingly accessible for ageing and less fit people. As a result, more and more individuals with varying degrees of respiratory conditions wish to travel to altitude destinations. Exposure to a hypobaric hypoxic environment at altitude challenges the human body and leads to a series of physiological adaptive mechanisms. These changes, as well as general altitude related risks have been well described in healthy individuals. However, limited data are available on the risks faced by patients with pre-existing lung disease. A comprehensive literature search was conducted. First, we aimed in this review to evaluate health risks of moderate and high terrestrial altitude travel by patients with pre-existing lung disease, including chronic obstructive pulmonary disease, sleep apnoea syndrome, asthma, bullous or cystic lung disease, pulmonary hypertension and interstitial lung disease. Second, we seek to summarise for each underlying lung disease, a personalized pre-travel assessment as well as measures to prevent, monitor and mitigate worsening of underlying respiratory disease during travel.https://doi.org/10.1186/s12890-022-01979-zChronic lung diseaseHigh altitude travelAir travelExercise performancePrediction toolsHypoxic tests
spellingShingle Kirsten Holthof
Pierre-Olivier Bridevaux
Isabelle Frésard
Underlying lung disease and exposure to terrestrial moderate and high altitude: personalised risk assessment
BMC Pulmonary Medicine
Chronic lung disease
High altitude travel
Air travel
Exercise performance
Prediction tools
Hypoxic tests
title Underlying lung disease and exposure to terrestrial moderate and high altitude: personalised risk assessment
title_full Underlying lung disease and exposure to terrestrial moderate and high altitude: personalised risk assessment
title_fullStr Underlying lung disease and exposure to terrestrial moderate and high altitude: personalised risk assessment
title_full_unstemmed Underlying lung disease and exposure to terrestrial moderate and high altitude: personalised risk assessment
title_short Underlying lung disease and exposure to terrestrial moderate and high altitude: personalised risk assessment
title_sort underlying lung disease and exposure to terrestrial moderate and high altitude personalised risk assessment
topic Chronic lung disease
High altitude travel
Air travel
Exercise performance
Prediction tools
Hypoxic tests
url https://doi.org/10.1186/s12890-022-01979-z
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AT isabellefresard underlyinglungdiseaseandexposuretoterrestrialmoderateandhighaltitudepersonalisedriskassessment