Evaluation of characteristics of CD44<sup>+</sup>CD117<sup>+</sup> ovarian cancer stem cells in three dimensional basement membrane extract scaffold versus two dimensional monocultures

Evaluation of characteristics of CD44<sup>+</sup>CD117<sup>+</sup> ovarian cancer stem cells in three dimensional basement membrane extract scaffold versus two dimensional monocultures

<p>Abstract</p> <p>Background</p> <p>Cancer stem cells (CSCs) are thought to be capable of surviving conventional chemotherapeutic treatments because the cells have more resistant to anticancer drugs than common cancer cells. Most <it>in vitro</it> studies i...

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Bibliographic Details
Main Authors: Chen Junsong, Wang Jing, Chen Dengyu, Yang Jie, Yang Cuiping, Zhang Yunxia, Zhang Hongyi, Dou Jun
Format: Article
Language:English
Published: BMC 2013-01-01
Series:BMC Cell Biology
Subjects:
Three-dimensional culture
Epithelial ovarian cancer
Cancer stem cells
Chemoresistance
Online Access:http://www.biomedcentral.com/1471-2121/14/7

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