A rare case of metastatic small cell neuroendocrine carcinoma of the lung presenting as isolated thrombocytopenia
Small cell neuroendocrine carcinoma (SNEC) is a high grade and poorly differentiated neuroendocrine tumor which typically presents as a primary pulmonary neoplasm near the bronchial region. Due to the aggressive nature of the tumor, there are many ways it can initially present, mostly involving the...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Greater Baltimore Medical Center
2019-07-01
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| Series: | Journal of Community Hospital Internal Medicine Perspectives |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/20009666.2019.1644916 |
| _version_ | 1797971831051780096 |
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| author | Adreana DeMarinis Fahad Malik Tommy Matin Zalmi Rahmany Tyler Putnam Jay Nfonoyim |
| author_facet | Adreana DeMarinis Fahad Malik Tommy Matin Zalmi Rahmany Tyler Putnam Jay Nfonoyim |
| author_sort | Adreana DeMarinis |
| collection | DOAJ |
| description | Small cell neuroendocrine carcinoma (SNEC) is a high grade and poorly differentiated neuroendocrine tumor which typically presents as a primary pulmonary neoplasm near the bronchial region. Due to the aggressive nature of the tumor, there are many ways it can initially present, mostly involving the lungs. We present a case of a 68-year-old male patient who initially presented with new-onset of severe thrombocytopenia with superimposed pneumonia. It was late in the progression of the disease that histopathology from the bone marrow confirmed SNEC, which presented only after it metastasized to the bone marrow by way of a rare paraneoplastic syndrome. Furthermore, the bone marrow biopsy revealed atypical markers not commonly seen in SNEC. Since this was such an atypical presentation of SNEC, management was limited to stabilization of the patient. The patient expired two weeks later. |
| first_indexed | 2024-04-11T03:37:43Z |
| format | Article |
| id | doaj.art-69ecffc35eef448093abccf39de9e7f2 |
| institution | Directory Open Access Journal |
| issn | 2000-9666 |
| language | English |
| last_indexed | 2024-04-11T03:37:43Z |
| publishDate | 2019-07-01 |
| publisher | Greater Baltimore Medical Center |
| record_format | Article |
| series | Journal of Community Hospital Internal Medicine Perspectives |
| spelling | doaj.art-69ecffc35eef448093abccf39de9e7f22023-01-02T04:39:30ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662019-07-019432732910.1080/20009666.2019.16449161644916A rare case of metastatic small cell neuroendocrine carcinoma of the lung presenting as isolated thrombocytopeniaAdreana DeMarinis0Fahad Malik1Tommy Matin2Zalmi Rahmany3Tyler Putnam4Jay Nfonoyim5Richmond University Medical CenterRichmond University Medical CenterRichmond University Medical CenterRichmond University Medical CenterSt. Joseph HospitalRichmond University Medical CenterSmall cell neuroendocrine carcinoma (SNEC) is a high grade and poorly differentiated neuroendocrine tumor which typically presents as a primary pulmonary neoplasm near the bronchial region. Due to the aggressive nature of the tumor, there are many ways it can initially present, mostly involving the lungs. We present a case of a 68-year-old male patient who initially presented with new-onset of severe thrombocytopenia with superimposed pneumonia. It was late in the progression of the disease that histopathology from the bone marrow confirmed SNEC, which presented only after it metastasized to the bone marrow by way of a rare paraneoplastic syndrome. Furthermore, the bone marrow biopsy revealed atypical markers not commonly seen in SNEC. Since this was such an atypical presentation of SNEC, management was limited to stabilization of the patient. The patient expired two weeks later.http://dx.doi.org/10.1080/20009666.2019.1644916Small cell neuroendocrine carcinomametastaticbone marrowcancer-related microangiopathic hemolytic anemiathrombocytopenia |
| spellingShingle | Adreana DeMarinis Fahad Malik Tommy Matin Zalmi Rahmany Tyler Putnam Jay Nfonoyim A rare case of metastatic small cell neuroendocrine carcinoma of the lung presenting as isolated thrombocytopenia Journal of Community Hospital Internal Medicine Perspectives Small cell neuroendocrine carcinoma metastatic bone marrow cancer-related microangiopathic hemolytic anemia thrombocytopenia |
| title | A rare case of metastatic small cell neuroendocrine carcinoma of the lung presenting as isolated thrombocytopenia |
| title_full | A rare case of metastatic small cell neuroendocrine carcinoma of the lung presenting as isolated thrombocytopenia |
| title_fullStr | A rare case of metastatic small cell neuroendocrine carcinoma of the lung presenting as isolated thrombocytopenia |
| title_full_unstemmed | A rare case of metastatic small cell neuroendocrine carcinoma of the lung presenting as isolated thrombocytopenia |
| title_short | A rare case of metastatic small cell neuroendocrine carcinoma of the lung presenting as isolated thrombocytopenia |
| title_sort | rare case of metastatic small cell neuroendocrine carcinoma of the lung presenting as isolated thrombocytopenia |
| topic | Small cell neuroendocrine carcinoma metastatic bone marrow cancer-related microangiopathic hemolytic anemia thrombocytopenia |
| url | http://dx.doi.org/10.1080/20009666.2019.1644916 |
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