A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 2; peer review: 2 approved]
Background Neonatal hyperbilirubinemia is one of the most common conditions for neonate inpatients. Indonesia faces a major challenge in which different guidelines regarding the management of this condition were present. This study aimed to compare the existing guidelines regarding prevention, diagn...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2023-11-01
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| Series: | F1000Research |
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| Online Access: | https://f1000research.com/articles/11-1534/v2 |
| _version_ | 1797449832216920064 |
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| author | Jordy Maulana Ahmad Setya Wandita Risma Karina Kaban Achmad Januar Er Putra Kian Djien Liem Rahmi Zakiyah Novita Oktaviana Danny Chandra Pratama Rinawati Rohsiswatmo Wurry Ayuningtyas Toto Wisnu Hendrarto Mahendra Tri Arif Sampurna Martono Tri Utomo Dina Angelica Risa Etika Kartika Darma Handayani Visuddho Visuddho |
| author_facet | Jordy Maulana Ahmad Setya Wandita Risma Karina Kaban Achmad Januar Er Putra Kian Djien Liem Rahmi Zakiyah Novita Oktaviana Danny Chandra Pratama Rinawati Rohsiswatmo Wurry Ayuningtyas Toto Wisnu Hendrarto Mahendra Tri Arif Sampurna Martono Tri Utomo Dina Angelica Risa Etika Kartika Darma Handayani Visuddho Visuddho |
| author_sort | Jordy Maulana Ahmad |
| collection | DOAJ |
| description | Background Neonatal hyperbilirubinemia is one of the most common conditions for neonate inpatients. Indonesia faces a major challenge in which different guidelines regarding the management of this condition were present. This study aimed to compare the existing guidelines regarding prevention, diagnosis, treatment and monitoring in order to create the best recommendation for a new hyperbilirubinemia guideline in Indonesia. Methods Through an earlier survey regarding adherence to the neonatal hyperbilirubinemia guideline, we identified that three main guidelines are being used in Indonesia. These were developed by the Indonesian Pediatric Society (IPS), the Ministry of Health (MoH), and World Health Organization (WHO). In this study, we compared factors such as prevention, monitoring, methods for identifying, risk factors in the development of neonatal jaundice, risk factors that increase brain damage, and intervention treatment threshold in the existing guidelines to determine the best recommendations for a new guideline. Results The MoH and WHO guidelines allow screening and treatment of hyperbilirubinemia based on visual examination (VE) only. Compared with the MoH and WHO guidelines, risk assessment is comprehensively discussed in the IPS guideline. The MoH guideline recommends further examination of an icteric baby to ensure that the mother has enough milk without measuring the bilirubin level. The MoH guideline recommends referring the baby when it looks yellow on the soles and palms. The WHO and IPS guidelines recommend combining VE with an objective measurement of transcutaneous or serum bilirubin. The threshold to begin phototherapy in the WHO guideline is lower than the IPS guideline while the exchange transfusion threshold in both guidelines are comparably equal. Conclusions The MoH guideline is outdated. MoH and IPS guidelines are causing differences in approaches to the management hyperbilirubinemia. A new, uniform guideline is required. |
| first_indexed | 2024-03-09T14:31:45Z |
| format | Article |
| id | doaj.art-69f77e770ea5480d89b0092ccdfd0810 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-03-09T14:31:45Z |
| publishDate | 2023-11-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-69f77e770ea5480d89b0092ccdfd08102023-11-28T01:00:02ZengF1000 Research LtdF1000Research2046-14022023-11-0111158223A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 2; peer review: 2 approved]Jordy Maulana Ahmad0Setya Wandita1Risma Karina Kaban2Achmad Januar Er Putra3Kian Djien Liem4https://orcid.org/0000-0001-9987-9104Rahmi Zakiyah5Novita Oktaviana6Danny Chandra Pratama7Rinawati Rohsiswatmo8Wurry Ayuningtyas9Toto Wisnu Hendrarto10https://orcid.org/0000-0002-7150-0753Mahendra Tri Arif Sampurna11https://orcid.org/0000-0002-7529-8142Martono Tri Utomo12Dina Angelica13Risa Etika14Kartika Darma Handayani15Visuddho Visuddho16https://orcid.org/0000-0002-6780-6207Medical Program, Faculty of Medicine, Universitas Airlangga, Surbaya, 60115, IndonesiaNeonatology Division, Department of Child Health, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, 55281, IndonesiaNeonatology Division, Department of Pediatrics, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, IndonesiaDepartment of Pediatrics, Airlangga University Teaching Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, 60115, IndonesiaDepartment of Neonatology, Radboud University Medical Centre, Nijmegen, 6525, Netherlands AntillesDepartment of Pediatrics, Airlangga University Teaching Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, 60115, IndonesiaDepartment of Pediatrics, Airlangga University Teaching Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, 60115, IndonesiaDepartment of Pediatrics, Airlangga University Teaching Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, 60115, IndonesiaNeonatology Division, Department of Pediatrics, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, IndonesiaNeonatology Division, Department of Pediatrics, Dr Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surbaya, 60115, IndonesiaNeonatal Intensive Care Unit, Harapan Kita Mother and Child Hospital, Jakarta, 11420, IndonesiaNeonatology Division, Department of Pediatrics, Dr Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surbaya, 60115, IndonesiaNeonatology Division, Department of Pediatrics, Dr Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surbaya, 60115, IndonesiaNeonatology Division, Department of Pediatrics, Dr Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surbaya, 60115, IndonesiaNeonatology Division, Department of Pediatrics, Dr Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surbaya, 60115, IndonesiaNeonatology Division, Department of Pediatrics, Dr Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surbaya, 60115, IndonesiaMedical Program, Faculty of Medicine, Universitas Airlangga, Surbaya, 60115, IndonesiaBackground Neonatal hyperbilirubinemia is one of the most common conditions for neonate inpatients. Indonesia faces a major challenge in which different guidelines regarding the management of this condition were present. This study aimed to compare the existing guidelines regarding prevention, diagnosis, treatment and monitoring in order to create the best recommendation for a new hyperbilirubinemia guideline in Indonesia. Methods Through an earlier survey regarding adherence to the neonatal hyperbilirubinemia guideline, we identified that three main guidelines are being used in Indonesia. These were developed by the Indonesian Pediatric Society (IPS), the Ministry of Health (MoH), and World Health Organization (WHO). In this study, we compared factors such as prevention, monitoring, methods for identifying, risk factors in the development of neonatal jaundice, risk factors that increase brain damage, and intervention treatment threshold in the existing guidelines to determine the best recommendations for a new guideline. Results The MoH and WHO guidelines allow screening and treatment of hyperbilirubinemia based on visual examination (VE) only. Compared with the MoH and WHO guidelines, risk assessment is comprehensively discussed in the IPS guideline. The MoH guideline recommends further examination of an icteric baby to ensure that the mother has enough milk without measuring the bilirubin level. The MoH guideline recommends referring the baby when it looks yellow on the soles and palms. The WHO and IPS guidelines recommend combining VE with an objective measurement of transcutaneous or serum bilirubin. The threshold to begin phototherapy in the WHO guideline is lower than the IPS guideline while the exchange transfusion threshold in both guidelines are comparably equal. Conclusions The MoH guideline is outdated. MoH and IPS guidelines are causing differences in approaches to the management hyperbilirubinemia. A new, uniform guideline is required.https://f1000research.com/articles/11-1534/v2icterus neonates recommendations LMIC eng |
| spellingShingle | Jordy Maulana Ahmad Setya Wandita Risma Karina Kaban Achmad Januar Er Putra Kian Djien Liem Rahmi Zakiyah Novita Oktaviana Danny Chandra Pratama Rinawati Rohsiswatmo Wurry Ayuningtyas Toto Wisnu Hendrarto Mahendra Tri Arif Sampurna Martono Tri Utomo Dina Angelica Risa Etika Kartika Darma Handayani Visuddho Visuddho A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 2; peer review: 2 approved] F1000Research icterus neonates recommendations LMIC eng |
| title | A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 2; peer review: 2 approved] |
| title_full | A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 2; peer review: 2 approved] |
| title_fullStr | A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 2; peer review: 2 approved] |
| title_full_unstemmed | A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 2; peer review: 2 approved] |
| title_short | A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 2; peer review: 2 approved] |
| title_sort | review of existing neonatal hyperbilirubinemia guidelines in indonesia version 2 peer review 2 approved |
| topic | icterus neonates recommendations LMIC eng |
| url | https://f1000research.com/articles/11-1534/v2 |
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