Occurrence of early adverse events after vaccination against influenza at a brazilian reference center

INTRODUCTION: Since 1999, the Ministry of Health in Brazil has conducted campaigns of vaccination against influenza targeted towards the elderly, chronically-diseased people and health care workers. The vaccine against influenza is associated with adverse events of minor importance. OBJECTIVE: To in...

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Main Authors: Marta Heloísa Lopes, Melissa Mascheretti, Marilia Miranda Franco, Ricardo Vasconcelos, Eliana Battaggia Gutierrez
Format: Article
Language:English
Published: Elsevier España 2008-01-01
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322008000100005
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author Marta Heloísa Lopes
Melissa Mascheretti
Marilia Miranda Franco
Ricardo Vasconcelos
Eliana Battaggia Gutierrez
author_facet Marta Heloísa Lopes
Melissa Mascheretti
Marilia Miranda Franco
Ricardo Vasconcelos
Eliana Battaggia Gutierrez
author_sort Marta Heloísa Lopes
collection DOAJ
description INTRODUCTION: Since 1999, the Ministry of Health in Brazil has conducted campaigns of vaccination against influenza targeted towards the elderly, chronically-diseased people and health care workers. The vaccine against influenza is associated with adverse events of minor importance. OBJECTIVE: To investigate the early adverse events related to the vaccine against influenza. CASUISTICS AND METHODS: One hundred and ninety seven elderly individuals and health care workers vaccinated against influenza were included. An inquiry regarding adverse events related to the vaccine was applied seven days after the vaccination. RESULTS: Local adverse events were reported by 32.5% and systemic effects by 26.4% of the vaccinated subjects. Pain in the region of the injection, headache, myalgia, malaise, and coryza were more frequent in the workers than in the elderly (p<0.05). There was no statistically significant difference in the occurrence of fever. CONCLUSIONS: The belief of part of the population that credits frequent and uncomfortable adverse events to the vaccine was not confirmed. The subjective adverse events were more frequent in the health care workers, which can influence, in a negative way, the disclosure of the benefits of this vaccine due to their role as opinion makers.
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spelling doaj.art-69f960ecf42a441cb487d876cb74fb972022-12-22T01:19:50ZengElsevier EspañaClinics1807-59321980-53222008-01-01631212610.1590/S1807-59322008000100005Occurrence of early adverse events after vaccination against influenza at a brazilian reference centerMarta Heloísa LopesMelissa MascherettiMarilia Miranda FrancoRicardo VasconcelosEliana Battaggia GutierrezINTRODUCTION: Since 1999, the Ministry of Health in Brazil has conducted campaigns of vaccination against influenza targeted towards the elderly, chronically-diseased people and health care workers. The vaccine against influenza is associated with adverse events of minor importance. OBJECTIVE: To investigate the early adverse events related to the vaccine against influenza. CASUISTICS AND METHODS: One hundred and ninety seven elderly individuals and health care workers vaccinated against influenza were included. An inquiry regarding adverse events related to the vaccine was applied seven days after the vaccination. RESULTS: Local adverse events were reported by 32.5% and systemic effects by 26.4% of the vaccinated subjects. Pain in the region of the injection, headache, myalgia, malaise, and coryza were more frequent in the workers than in the elderly (p<0.05). There was no statistically significant difference in the occurrence of fever. CONCLUSIONS: The belief of part of the population that credits frequent and uncomfortable adverse events to the vaccine was not confirmed. The subjective adverse events were more frequent in the health care workers, which can influence, in a negative way, the disclosure of the benefits of this vaccine due to their role as opinion makers.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322008000100005Influenza vaccineAdverse eventsElderlyHealth care workers
spellingShingle Marta Heloísa Lopes
Melissa Mascheretti
Marilia Miranda Franco
Ricardo Vasconcelos
Eliana Battaggia Gutierrez
Occurrence of early adverse events after vaccination against influenza at a brazilian reference center
Clinics
Influenza vaccine
Adverse events
Elderly
Health care workers
title Occurrence of early adverse events after vaccination against influenza at a brazilian reference center
title_full Occurrence of early adverse events after vaccination against influenza at a brazilian reference center
title_fullStr Occurrence of early adverse events after vaccination against influenza at a brazilian reference center
title_full_unstemmed Occurrence of early adverse events after vaccination against influenza at a brazilian reference center
title_short Occurrence of early adverse events after vaccination against influenza at a brazilian reference center
title_sort occurrence of early adverse events after vaccination against influenza at a brazilian reference center
topic Influenza vaccine
Adverse events
Elderly
Health care workers
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322008000100005
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