Comprehensive phenotyping of cutaneous afferents reveals early-onset alterations in nociceptor response properties, release of CGRP, and hindpaw edema following spinal cord injury

Comprehensive phenotyping of cutaneous afferents reveals early-onset alterations in nociceptor response properties, release of CGRP, and hindpaw edema following spinal cord injury

Spinal cord injury (SCI) is a complex syndrome that has profound effects on patient well-being, including the development of medically-resistant chronic pain. The mechanisms underlying SCI pain have been the subject of thorough investigation but remain poorly understood. While the majority of the re...

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Bibliographic Details
Main Authors: Olivia C. Eller, Rena N. Stair, Christopher Neal, Peter S.N. Rowe, Jennifer Nelson-Brantley, Erin E. Young, Kyle M. Baumbauer
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Neurobiology of Pain
Subjects:
Acute spinal cord injury
Below level
Pain
DRG
Sensory neuron
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2452073X22000149

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