Pathognomonic neuroimaging of a Multinodular and Vacuolating Neuronal Tumor of the Cerebrum incidentally discovered in an 8-year old female. A case report
Background. The WHO 2016 classification of tumors of the CNS includes Multinodular and Vacuolating Neuronal Tumors (MVNT) as a benign ganglion cell tumor, possibly associated with seizures. MTVN pathologic hallmark to be consisting of a “subcortical cluster of nodular lesions located on the inner su...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Amaltea Medical Publishing House
2023-09-01
|
| Series: | Romanian Journal of Neurology |
| Subjects: | |
| Online Access: | https://rjn.com.ro/articles/2023.3/RJN_2023_3_Art-06.pdf |
| _version_ | 1797354091480875008 |
|---|---|
| author | Luigi Di Lorenzo Serena Schipani Marina Minichiello Franco Carmine Muccio |
| author_facet | Luigi Di Lorenzo Serena Schipani Marina Minichiello Franco Carmine Muccio |
| author_sort | Luigi Di Lorenzo |
| collection | DOAJ |
| description | Background. The WHO 2016 classification of tumors of the CNS includes Multinodular and Vacuolating Neuronal Tumors (MVNT) as a benign ganglion cell tumor, possibly associated with seizures. MTVN pathologic hallmark to be consisting of a “subcortical cluster of nodular lesions located on the inner surface of an otherwise normal appearing cortex, within the deep cortical ribbon and superficial subcortical white matter”. MVNT is mostly present in adults.
Case report. In this case, we report pathognomonic pics of MVNT in a noticeably rare young patient, where it was unclear whether MVNTs should be considered a true neoplasm or malformative lesion, that typically occurs causing seizures
Conclusion. It confirms nowadays that in clinical practice the MRI can help neurosurgeons to confirm the clinical non-surgical diagnosis even if in the lack of more common symptoms such as seizures. |
| first_indexed | 2024-03-08T13:40:17Z |
| format | Article |
| id | doaj.art-69fd78bef3804f2b9782a7e3844ad3b8 |
| institution | Directory Open Access Journal |
| issn | 1843-8148 2069-6094 |
| language | English |
| last_indexed | 2024-03-08T13:40:17Z |
| publishDate | 2023-09-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Neurology |
| spelling | doaj.art-69fd78bef3804f2b9782a7e3844ad3b82024-01-16T11:19:17ZengAmaltea Medical Publishing HouseRomanian Journal of Neurology1843-81482069-60942023-09-0122325826010.37897/RJN.2023.3.6Pathognomonic neuroimaging of a Multinodular and Vacuolating Neuronal Tumor of the Cerebrum incidentally discovered in an 8-year old female. A case reportLuigi Di Lorenzo0Serena Schipani1Marina Minichiello2Franco Carmine Muccio3Mebic Consorzio, San Raffaele Cassino, ItalyNeuro-Radiology Unit, San Pio Hospital, Benevento, ItalyNeurosurgery Unit, San Pio Hospital, Benevento, ItalyNeuro-Radiology Unit, San Pio Hospital, Benevento, ItalyBackground. The WHO 2016 classification of tumors of the CNS includes Multinodular and Vacuolating Neuronal Tumors (MVNT) as a benign ganglion cell tumor, possibly associated with seizures. MTVN pathologic hallmark to be consisting of a “subcortical cluster of nodular lesions located on the inner surface of an otherwise normal appearing cortex, within the deep cortical ribbon and superficial subcortical white matter”. MVNT is mostly present in adults. Case report. In this case, we report pathognomonic pics of MVNT in a noticeably rare young patient, where it was unclear whether MVNTs should be considered a true neoplasm or malformative lesion, that typically occurs causing seizures Conclusion. It confirms nowadays that in clinical practice the MRI can help neurosurgeons to confirm the clinical non-surgical diagnosis even if in the lack of more common symptoms such as seizures.https://rjn.com.ro/articles/2023.3/RJN_2023_3_Art-06.pdfmultinodular and vacuolating neuronal tumorsbrain tumor mrichildren brain tumor mri |
| spellingShingle | Luigi Di Lorenzo Serena Schipani Marina Minichiello Franco Carmine Muccio Pathognomonic neuroimaging of a Multinodular and Vacuolating Neuronal Tumor of the Cerebrum incidentally discovered in an 8-year old female. A case report Romanian Journal of Neurology multinodular and vacuolating neuronal tumors brain tumor mri children brain tumor mri |
| title | Pathognomonic neuroimaging of a Multinodular and Vacuolating Neuronal Tumor of the Cerebrum incidentally discovered in an 8-year old female. A case report |
| title_full | Pathognomonic neuroimaging of a Multinodular and Vacuolating Neuronal Tumor of the Cerebrum incidentally discovered in an 8-year old female. A case report |
| title_fullStr | Pathognomonic neuroimaging of a Multinodular and Vacuolating Neuronal Tumor of the Cerebrum incidentally discovered in an 8-year old female. A case report |
| title_full_unstemmed | Pathognomonic neuroimaging of a Multinodular and Vacuolating Neuronal Tumor of the Cerebrum incidentally discovered in an 8-year old female. A case report |
| title_short | Pathognomonic neuroimaging of a Multinodular and Vacuolating Neuronal Tumor of the Cerebrum incidentally discovered in an 8-year old female. A case report |
| title_sort | pathognomonic neuroimaging of a multinodular and vacuolating neuronal tumor of the cerebrum incidentally discovered in an 8 year old female a case report |
| topic | multinodular and vacuolating neuronal tumors brain tumor mri children brain tumor mri |
| url | https://rjn.com.ro/articles/2023.3/RJN_2023_3_Art-06.pdf |
| work_keys_str_mv | AT luigidilorenzo pathognomonicneuroimagingofamultinodularandvacuolatingneuronaltumorofthecerebrumincidentallydiscoveredinan8yearoldfemaleacasereport AT serenaschipani pathognomonicneuroimagingofamultinodularandvacuolatingneuronaltumorofthecerebrumincidentallydiscoveredinan8yearoldfemaleacasereport AT marinaminichiello pathognomonicneuroimagingofamultinodularandvacuolatingneuronaltumorofthecerebrumincidentallydiscoveredinan8yearoldfemaleacasereport AT francocarminemuccio pathognomonicneuroimagingofamultinodularandvacuolatingneuronaltumorofthecerebrumincidentallydiscoveredinan8yearoldfemaleacasereport |