Undernutrition when young and the risk of poor renal function in adulthood in women with diabetes in Shanghai, China
Objective To evaluate the effect of undernutrition when young on the risk of poor renal function in adulthood in women with diabetes mellitus. Methods We studied diabetic women born between 1921 and 1958 who were exposed to the 1959-to-1962 Chinese famine when they were 0 to 37 years old. Exposure a...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2021-05-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605211016671 |
| _version_ | 1818578354347966464 |
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| author | Qiaojing Qin Kaili Chang Qing Wu Weifeng Fan Yong Gu Jianying Niu Xueguang Liu |
| author_facet | Qiaojing Qin Kaili Chang Qing Wu Weifeng Fan Yong Gu Jianying Niu Xueguang Liu |
| author_sort | Qiaojing Qin |
| collection | DOAJ |
| description | Objective To evaluate the effect of undernutrition when young on the risk of poor renal function in adulthood in women with diabetes mellitus. Methods We studied diabetic women born between 1921 and 1958 who were exposed to the 1959-to-1962 Chinese famine when they were 0 to 37 years old. Exposure age was classified as young adulthood (18 to 37 years), adolescence (10 to 17 years), or childhood (0 to 9 years). The Adolescence group, which was provided with the largest amount of food during the famine, was used as the control group, and variance and binary logistic regression analyses were performed. Results The prevalences of low estimated glomerular filtration rate (eGFR) in the Childhood, Adolescence, and Young adulthood groups were 5.26%, 22.39%, and 79.24%, respectively. The risk of low eGFR for the Young adulthood group (odds ratio [OR] 1.65, 95% confidence interval [CI] 1.10, 2.48), but not for the Childhood group (OR 1.10, 95% CI 0.68, 1.78), was higher than that for the Adolescence group after adjustment for potential confounders. Conclusions Undernutrition during young adulthood significantly increases the risk of renal dysfunction in adult women with diabetes. Therefore, the nutrition of less affluent young women should be improved. |
| first_indexed | 2024-12-16T06:44:28Z |
| format | Article |
| id | doaj.art-6a01bbf206654ff5850ccb26718b46e0 |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-12-16T06:44:28Z |
| publishDate | 2021-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-6a01bbf206654ff5850ccb26718b46e02022-12-21T22:40:35ZengSAGE PublishingJournal of International Medical Research1473-23002021-05-014910.1177/03000605211016671Undernutrition when young and the risk of poor renal function in adulthood in women with diabetes in Shanghai, ChinaQiaojing QinKaili ChangQing WuWeifeng FanYong GuJianying NiuXueguang LiuObjective To evaluate the effect of undernutrition when young on the risk of poor renal function in adulthood in women with diabetes mellitus. Methods We studied diabetic women born between 1921 and 1958 who were exposed to the 1959-to-1962 Chinese famine when they were 0 to 37 years old. Exposure age was classified as young adulthood (18 to 37 years), adolescence (10 to 17 years), or childhood (0 to 9 years). The Adolescence group, which was provided with the largest amount of food during the famine, was used as the control group, and variance and binary logistic regression analyses were performed. Results The prevalences of low estimated glomerular filtration rate (eGFR) in the Childhood, Adolescence, and Young adulthood groups were 5.26%, 22.39%, and 79.24%, respectively. The risk of low eGFR for the Young adulthood group (odds ratio [OR] 1.65, 95% confidence interval [CI] 1.10, 2.48), but not for the Childhood group (OR 1.10, 95% CI 0.68, 1.78), was higher than that for the Adolescence group after adjustment for potential confounders. Conclusions Undernutrition during young adulthood significantly increases the risk of renal dysfunction in adult women with diabetes. Therefore, the nutrition of less affluent young women should be improved.https://doi.org/10.1177/03000605211016671 |
| spellingShingle | Qiaojing Qin Kaili Chang Qing Wu Weifeng Fan Yong Gu Jianying Niu Xueguang Liu Undernutrition when young and the risk of poor renal function in adulthood in women with diabetes in Shanghai, China Journal of International Medical Research |
| title | Undernutrition when young and the risk of poor renal function in adulthood in women with diabetes in Shanghai, China |
| title_full | Undernutrition when young and the risk of poor renal function in adulthood in women with diabetes in Shanghai, China |
| title_fullStr | Undernutrition when young and the risk of poor renal function in adulthood in women with diabetes in Shanghai, China |
| title_full_unstemmed | Undernutrition when young and the risk of poor renal function in adulthood in women with diabetes in Shanghai, China |
| title_short | Undernutrition when young and the risk of poor renal function in adulthood in women with diabetes in Shanghai, China |
| title_sort | undernutrition when young and the risk of poor renal function in adulthood in women with diabetes in shanghai china |
| url | https://doi.org/10.1177/03000605211016671 |
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