Associations of depression and regional brain structure across the adult lifespan: Pooled analyses of six population-based and two clinical cohort studies in the European Lifebrain consortium

Associations of depression and regional brain structure across the adult lifespan: Pooled analyses of six population-based and two clinical cohort studies in the European Lifebrain consortium

Objective: Major depressive disorder has been associated with lower prefrontal thickness and hippocampal volume, but it is unknown whether this association also holds for depressive symptoms in the general population. We investigated associations of depressive symptoms and depression status with bra...

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Main Authors: Julia Binnewies, Laura Nawijn, Andreas M. Brandmaier, William F.C. Baaré, David Bartrés-Faz, Christian A. Drevon, Sandra Düzel, Anders M. Fjell, Laura K.M. Han, Ethan Knights, Ulman Lindenberger, Yuri Milaneschi, Athanasia M. Mowinckel, Lars Nyberg, Anna Plachti, Kathrine Skak Madsen, Cristina Solé-Padullés, Sana Suri, Kristine B. Walhovd, Enikő Zsoldos, Klaus P. Ebmeier, Brenda W.J.H. Penninx
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:NeuroImage: Clinical
Subjects:
Neuroimaging
Depressive symptoms
Meta-analysis
Lifespan
Grey matter
Brain structure
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158222002455

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