Specific cognitive domains and symptoms of depression as predictors of activities of daily living in older adults with heterogeneous cognitive backgrounds
Cognitive functioning play an important role in the performance of activities of daily living (ADL). Although and association between this two measures are usually reported in neuropsychological studies, the results are inconsistent, especially in what aspects cognitive functioning are more or less...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2015-07-01
|
| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00139/full |
| _version_ | 1818247727005302784 |
|---|---|
| author | Jonas Jardim de Paula Jonas Jardim de Paula Breno Satler Diniz Breno Satler Diniz Maria Aparecida eBicalho Maria Aparecida eBicalho Maicon eAlbuquerque Maicon eAlbuquerque Rodrigo eNicolato Edgar Nunes Moraes Marco Aurélio Romano-Silva Marco Aurélio Romano-Silva Leandro Fernandes Malloy-Diniz Leandro Fernandes Malloy-Diniz |
| author_facet | Jonas Jardim de Paula Jonas Jardim de Paula Breno Satler Diniz Breno Satler Diniz Maria Aparecida eBicalho Maria Aparecida eBicalho Maicon eAlbuquerque Maicon eAlbuquerque Rodrigo eNicolato Edgar Nunes Moraes Marco Aurélio Romano-Silva Marco Aurélio Romano-Silva Leandro Fernandes Malloy-Diniz Leandro Fernandes Malloy-Diniz |
| author_sort | Jonas Jardim de Paula |
| collection | DOAJ |
| description | Cognitive functioning play an important role in the performance of activities of daily living (ADL). Although and association between this two measures are usually reported in neuropsychological studies, the results are inconsistent, especially in what aspects cognitive functioning are more or less related to each functional aspect. In addition, only a few studies investigated if depressive symptoms are associated with worse functional performance in older adults. Our objective is to investigate the role of different cognitive functions and the depressive symptoms in the performance of different groups of ADL and each activity individually. We assessed 264 older adults (96 normal aging controls, 85 patients diagnosed with mild cognitive impairment and 93 with mild probable Alzheimer’s disease dementia) with low formal education (about 4 years). We used measures of ADL with different levels of complexity: Selfcare, Instrumental-Domestic and Instrumental Complex, along with composite factors of cognitive functions and the score of the Geriatric Depression Scale. Multiple linear regression analysis showed significant predictors of Instrumental-Domestic ADL (executive functions and episodic memory) and Instrumental-Complex ADL (executive functions, episodic memory and language/semantic memory), with large effect sizes (22 and 28% of explained variance). Individual analysis of each Instrumental ADL shows a heterogeneous pattern of association with different cognitive factors and depressive symptoms, with effect sizes ranging from 22 to 38% of explained variance. Our results suggest that specific measures of ADL have different cognitive predictors and that depressive symptoms are associated with activities more dependent on social contact. |
| first_indexed | 2024-12-12T15:09:18Z |
| format | Article |
| id | doaj.art-6a040218faab48d2b15cd12a221d7f22 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-12-12T15:09:18Z |
| publishDate | 2015-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-6a040218faab48d2b15cd12a221d7f222022-12-22T00:20:39ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652015-07-01710.3389/fnagi.2015.00139137009Specific cognitive domains and symptoms of depression as predictors of activities of daily living in older adults with heterogeneous cognitive backgroundsJonas Jardim de Paula0Jonas Jardim de Paula1Breno Satler Diniz2Breno Satler Diniz3Maria Aparecida eBicalho4Maria Aparecida eBicalho5Maicon eAlbuquerque6Maicon eAlbuquerque7Rodrigo eNicolato8Edgar Nunes Moraes9Marco Aurélio Romano-Silva10Marco Aurélio Romano-Silva11Leandro Fernandes Malloy-Diniz12Leandro Fernandes Malloy-Diniz13Universidade Federal de Minas GeraisFaculdade de Ciências Médicas de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de ViçosaUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisCognitive functioning play an important role in the performance of activities of daily living (ADL). Although and association between this two measures are usually reported in neuropsychological studies, the results are inconsistent, especially in what aspects cognitive functioning are more or less related to each functional aspect. In addition, only a few studies investigated if depressive symptoms are associated with worse functional performance in older adults. Our objective is to investigate the role of different cognitive functions and the depressive symptoms in the performance of different groups of ADL and each activity individually. We assessed 264 older adults (96 normal aging controls, 85 patients diagnosed with mild cognitive impairment and 93 with mild probable Alzheimer’s disease dementia) with low formal education (about 4 years). We used measures of ADL with different levels of complexity: Selfcare, Instrumental-Domestic and Instrumental Complex, along with composite factors of cognitive functions and the score of the Geriatric Depression Scale. Multiple linear regression analysis showed significant predictors of Instrumental-Domestic ADL (executive functions and episodic memory) and Instrumental-Complex ADL (executive functions, episodic memory and language/semantic memory), with large effect sizes (22 and 28% of explained variance). Individual analysis of each Instrumental ADL shows a heterogeneous pattern of association with different cognitive factors and depressive symptoms, with effect sizes ranging from 22 to 38% of explained variance. Our results suggest that specific measures of ADL have different cognitive predictors and that depressive symptoms are associated with activities more dependent on social contact.http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00139/fullActivities of Daily LivingDementiaDepressionMild Cognitive ImpairmentNeuropsychological TestsAlzheimer's disease |
| spellingShingle | Jonas Jardim de Paula Jonas Jardim de Paula Breno Satler Diniz Breno Satler Diniz Maria Aparecida eBicalho Maria Aparecida eBicalho Maicon eAlbuquerque Maicon eAlbuquerque Rodrigo eNicolato Edgar Nunes Moraes Marco Aurélio Romano-Silva Marco Aurélio Romano-Silva Leandro Fernandes Malloy-Diniz Leandro Fernandes Malloy-Diniz Specific cognitive domains and symptoms of depression as predictors of activities of daily living in older adults with heterogeneous cognitive backgrounds Frontiers in Aging Neuroscience Activities of Daily Living Dementia Depression Mild Cognitive Impairment Neuropsychological Tests Alzheimer's disease |
| title | Specific cognitive domains and symptoms of depression as predictors of activities of daily living in older adults with heterogeneous cognitive backgrounds |
| title_full | Specific cognitive domains and symptoms of depression as predictors of activities of daily living in older adults with heterogeneous cognitive backgrounds |
| title_fullStr | Specific cognitive domains and symptoms of depression as predictors of activities of daily living in older adults with heterogeneous cognitive backgrounds |
| title_full_unstemmed | Specific cognitive domains and symptoms of depression as predictors of activities of daily living in older adults with heterogeneous cognitive backgrounds |
| title_short | Specific cognitive domains and symptoms of depression as predictors of activities of daily living in older adults with heterogeneous cognitive backgrounds |
| title_sort | specific cognitive domains and symptoms of depression as predictors of activities of daily living in older adults with heterogeneous cognitive backgrounds |
| topic | Activities of Daily Living Dementia Depression Mild Cognitive Impairment Neuropsychological Tests Alzheimer's disease |
| url | http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00139/full |
| work_keys_str_mv | AT jonasjardimdepaula specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT jonasjardimdepaula specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT brenosatlerdiniz specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT brenosatlerdiniz specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT mariaaparecidaebicalho specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT mariaaparecidaebicalho specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT maiconealbuquerque specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT maiconealbuquerque specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT rodrigoenicolato specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT edgarnunesmoraes specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT marcoaurelioromanosilva specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT marcoaurelioromanosilva specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT leandrofernandesmalloydiniz specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds AT leandrofernandesmalloydiniz specificcognitivedomainsandsymptomsofdepressionaspredictorsofactivitiesofdailylivinginolderadultswithheterogeneouscognitivebackgrounds |