Tuberculosis infectious pool and associated factors in East Gojjam Zone, Northwest Ethiopia
Abstract Background Globally, tuberculosis (TB) lasts a major public health concern. Using feasible strategies to estimate TB infectious periods is crucial. The aim of this study was to determine the magnitude of TB infectious period and associated factors in East Gojjam zone. Methods An institution...
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| Format: | Article |
| Language: | English |
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BMC
2019-11-01
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| Series: | BMC Pulmonary Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12890-019-0995-3 |
| _version_ | 1819282554732150784 |
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| author | Mulusew Andualem Asemahagn Getu Degu Alene Solomon Abebe Yimer |
| author_facet | Mulusew Andualem Asemahagn Getu Degu Alene Solomon Abebe Yimer |
| author_sort | Mulusew Andualem Asemahagn |
| collection | DOAJ |
| description | Abstract Background Globally, tuberculosis (TB) lasts a major public health concern. Using feasible strategies to estimate TB infectious periods is crucial. The aim of this study was to determine the magnitude of TB infectious period and associated factors in East Gojjam zone. Methods An institution-based prospective study was conducted among 348 pulmonary TB (PTB) cases between December 2017 and December 2018. TB cases were recruited from all health facilities located in Hulet Eju Enesie, Enebse Sarmider, Debay Tilatgen, Dejen, Debre-Markos town administration, and Machakel districts. Data were collected through an exit interview using a structured questionnaire and analyzed by IBM SPSS version25. The TB infectious period of each patient category was determined using the TB management time and sputum smear conversion time. The sum of the infectious period of each patient category gave the infectious pool of the study area. A multivariable logistic regression analysis was used to identify factors associated with the magnitude of TB infectious period. Results Of the total participated PTB cases, 209(60%) were male, 226(65%) aged < 30 years, 205(59%) were from the rural settings, and 77 (22%) had comorbidities. The magnitude of the TB infectious pool in the study area was 78,031 infectious person-days. The undiagnosed TB cases (44,895 days), smear-positive (14,625 days) and smear-negative (12,995 days) were major contributors to the infectious pool. The overall average median TB management time was 142.4 days (IQR, 98–238 days). Similarly, the average sputum smear conversion time of PTB cases (new and repeat) was 46 days. Residence, knowledge, form of TB, smoking, alcohol history, distance from the facility, comorbidity history and stigma were statistically significant factors TB infectious period (p-value< 0.05). Conclusions The magnitude of the TB infectious pool is high even if it is lower than the findings of previous studies. This might be an indicator of poor access to TB services, service delays, low community awareness, impaired facility readiness, and poor transportation. Improving personal awareness and behavior, timely management of commodities, and using the TB management time in TB control are crucial to improving TB control activities. |
| first_indexed | 2024-12-24T01:17:26Z |
| format | Article |
| id | doaj.art-6a0760515b794593a88a020653ad6a8b |
| institution | Directory Open Access Journal |
| issn | 1471-2466 |
| language | English |
| last_indexed | 2024-12-24T01:17:26Z |
| publishDate | 2019-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pulmonary Medicine |
| spelling | doaj.art-6a0760515b794593a88a020653ad6a8b2022-12-21T17:22:45ZengBMCBMC Pulmonary Medicine1471-24662019-11-0119111110.1186/s12890-019-0995-3Tuberculosis infectious pool and associated factors in East Gojjam Zone, Northwest EthiopiaMulusew Andualem Asemahagn0Getu Degu Alene1Solomon Abebe Yimer2School of Public Health, College of Medicine and Health Sciences, Bahir Dar UniversitySchool of Public Health, College of Medicine and Health Sciences, Bahir Dar UniversityDepartment of Microbiology, Unit for Genome Dynamics, Faculty of Medicine, University of OsloAbstract Background Globally, tuberculosis (TB) lasts a major public health concern. Using feasible strategies to estimate TB infectious periods is crucial. The aim of this study was to determine the magnitude of TB infectious period and associated factors in East Gojjam zone. Methods An institution-based prospective study was conducted among 348 pulmonary TB (PTB) cases between December 2017 and December 2018. TB cases were recruited from all health facilities located in Hulet Eju Enesie, Enebse Sarmider, Debay Tilatgen, Dejen, Debre-Markos town administration, and Machakel districts. Data were collected through an exit interview using a structured questionnaire and analyzed by IBM SPSS version25. The TB infectious period of each patient category was determined using the TB management time and sputum smear conversion time. The sum of the infectious period of each patient category gave the infectious pool of the study area. A multivariable logistic regression analysis was used to identify factors associated with the magnitude of TB infectious period. Results Of the total participated PTB cases, 209(60%) were male, 226(65%) aged < 30 years, 205(59%) were from the rural settings, and 77 (22%) had comorbidities. The magnitude of the TB infectious pool in the study area was 78,031 infectious person-days. The undiagnosed TB cases (44,895 days), smear-positive (14,625 days) and smear-negative (12,995 days) were major contributors to the infectious pool. The overall average median TB management time was 142.4 days (IQR, 98–238 days). Similarly, the average sputum smear conversion time of PTB cases (new and repeat) was 46 days. Residence, knowledge, form of TB, smoking, alcohol history, distance from the facility, comorbidity history and stigma were statistically significant factors TB infectious period (p-value< 0.05). Conclusions The magnitude of the TB infectious pool is high even if it is lower than the findings of previous studies. This might be an indicator of poor access to TB services, service delays, low community awareness, impaired facility readiness, and poor transportation. Improving personal awareness and behavior, timely management of commodities, and using the TB management time in TB control are crucial to improving TB control activities.https://doi.org/10.1186/s12890-019-0995-3TB management timeTB infectious poolFactorsEast Gojjam zoneEthiopia |
| spellingShingle | Mulusew Andualem Asemahagn Getu Degu Alene Solomon Abebe Yimer Tuberculosis infectious pool and associated factors in East Gojjam Zone, Northwest Ethiopia BMC Pulmonary Medicine TB management time TB infectious pool Factors East Gojjam zone Ethiopia |
| title | Tuberculosis infectious pool and associated factors in East Gojjam Zone, Northwest Ethiopia |
| title_full | Tuberculosis infectious pool and associated factors in East Gojjam Zone, Northwest Ethiopia |
| title_fullStr | Tuberculosis infectious pool and associated factors in East Gojjam Zone, Northwest Ethiopia |
| title_full_unstemmed | Tuberculosis infectious pool and associated factors in East Gojjam Zone, Northwest Ethiopia |
| title_short | Tuberculosis infectious pool and associated factors in East Gojjam Zone, Northwest Ethiopia |
| title_sort | tuberculosis infectious pool and associated factors in east gojjam zone northwest ethiopia |
| topic | TB management time TB infectious pool Factors East Gojjam zone Ethiopia |
| url | https://doi.org/10.1186/s12890-019-0995-3 |
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