Characterization of the biological and transcriptomic landscapes of bone marrow-derived mesenchymal stem cells in patients with multiple myeloma

Characterization of the biological and transcriptomic landscapes of bone marrow-derived mesenchymal stem cells in patients with multiple myeloma

Abstract Background Mesenchymal stem/stromal cells (MSCs) have been acknowledged as the most important stromal cells in the bone marrow (BM) microenvironment for physiologic hematopoiesis and the concomitant hematologic malignancies. However, the systematic and detailed dissection of the biological...

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Bibliographic Details
Main Authors: Yu Lu, Chaohui Zheng, Wenxia Zhang, Xuan Liu, Ziwei Zhou, Zhenzhen Wang, Huan Hua, Zhengrong Song, Xuejun Zhang, Shuyi Liu, Leisheng Zhang, Fuxu Wang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Cancer Cell International
Subjects:
Multiple myeloma (MM)
BM-MSCs
Biological signatures
Transcriptomic variation
Cellular viability
Online Access:https://doi.org/10.1186/s12935-024-03308-2

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